C₁₈H₁₃ClN₂S

Base Information

• Chemical Name: C₁₈H₁₃ClN₂S
• CAS No.: 1353579-47-1
• Molecular Formula: C₁₈H₁₃ClN₂S
• Molecular Weight: 324.834
• Mol file: 1353579-47-1.mol

Synonyms:

Chemical Property of C₁₈H₁₃ClN₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₃ClN₂S

There total 6 articles about C₁₈H₁₃ClN₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H15ClN2O2 → C18H13ClN2S (1353579-47-1)

Guidance literature:

With tetraphosphorus decasulfide; In pyridine; at 80 ℃; for 2h;

DOI:10.1002/cmdc.201100309

Reference yield:

4-chloro-aniline (106-47-8) → C18H13ClN2S (1353579-47-1)

Guidance literature:

Multi-step reaction with 6 steps

1: acetic acid / toluene / 2 h / Reflux

2: diphenylether / 1 h / 240 °C

3: nitric acid; propionic acid / 2.33 h / 110 °C

4: iron; ammonium chloride / ethanol; water / Reflux

5: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C

6: tetraphosphorus decasulfide / pyridine / 2 h / 80 °C

With tetraphosphorus decasulfide; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; nitric acid; iron; ammonium chloride; acetic acid; propionic acid; N-ethyl-N,N-diisopropylamine; In pyridine; diphenylether; ethanol; water; N,N-dimethyl-formamide; toluene;

DOI:10.1002/cmdc.201100309

Reference yield:

C12H14ClNO2 (187386-90-9) → C18H13ClN2S (1353579-47-1)

Guidance literature:

Multi-step reaction with 5 steps

1: diphenylether / 1 h / 240 °C

2: nitric acid; propionic acid / 2.33 h / 110 °C

3: iron; ammonium chloride / ethanol; water / Reflux

4: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C

5: tetraphosphorus decasulfide / pyridine / 2 h / 80 °C

With tetraphosphorus decasulfide; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; nitric acid; iron; ammonium chloride; propionic acid; N-ethyl-N,N-diisopropylamine; In pyridine; diphenylether; ethanol; water; N,N-dimethyl-formamide;

DOI:10.1002/cmdc.201100309

upstream raw materials:

C₁₂H₁₄ClNO₂

C₁₀H₇ClN₂O₃

3-amino-6-chloro-2-methyl-4-quinolinol

p-Toluic acid