N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide

Base Information

Chemical Name:N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide
CAS No.:119514-95-3
Molecular Formula:C₂₆H₂₄N₂O₄S
Molecular Weight:460.554
Hs Code.:

Synonyms:

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Chemical Property of N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide

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Technology Process of N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide

There total 5 articles about N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4377-41-7
2-Chloromethylquinoline

: 119514-95-3
N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: cesium carbonate, potassium iodide / acetone / Heating

2: 1 N NaOH / tetrahydrofuran / Heating

3: 1.) 1,1-carbonyldiimidazole / 1.) THF, 1 h

With sodium hydroxide; caesium carbonate; 1,1'-carbonyldiimidazole; potassium iodide; In tetrahydrofuran; acetone;
DOI:10.1021/jm00163a039

Reference yield:

: 621-54-5
3-(3-hydroxyphenyl)-propanoic acid

: 119514-95-3
N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 25 wt percent NaOCH₃ / 1.) MeOH, 1 h, 2.) DMF, RT, 48 h

2: 100 percent / 1 N NaOH / tetrahydrofuran / 3 h / Heating

3: 1.) 1,1-carbonyldiimidazole / 1.) THF, 1 h

With sodium hydroxide; sodium methylate; 1,1'-carbonyldiimidazole; In tetrahydrofuran;
DOI:10.1021/jm00163a039

Reference yield:

: 61389-68-2
methyl 3-(3-hydroxyphenyl)propionate

: 119514-95-3
N-<(4-methylphenyl)sulfonyl>-3-(2-quinolinylmethoxy)benzenepropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: cesium carbonate, potassium iodide / acetone / Heating

2: 1 N NaOH / tetrahydrofuran / Heating

3: 1.) 1,1-carbonyldiimidazole / 1.) THF, 1 h

With sodium hydroxide; caesium carbonate; 1,1'-carbonyldiimidazole; potassium iodide; In tetrahydrofuran; acetone;
DOI:10.1021/jm00163a039