Technology Process of (2S)-1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphe
pin-4-yl-1,2,3,4-tetrahydro-2-methylquinoline,99%e.e.
There total 4 articles about (2S)-1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphe
pin-4-yl-1,2,3,4-tetrahydro-2-methylquinoline,99%e.e. which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(R)-1,2,3,4-tetrahydroquinaldine;
With
triethylamine; trichlorophosphate;
In
toluene;
at 0 - 80 ℃;
for 6h;
(S)-[1,1']-binaphthalenyl-2,2'-diol;
In
tetrahydrofuran; toluene;
at 0 - 20 ℃;
DOI:10.1002/anie.202102862
- Guidance literature:
-
(R)-1,2,3,4-tetrahydroquinaldine;
With
triethylamine; phosphorus trichloride;
In
toluene;
at 0 - 80 ℃;
for 6h;
Inert atmosphere;
(R)-(+)-2,2'bis(diphenylphosphino)-1,1'-binaphthalene;
With
triethylamine;
In
tetrahydrofuran; toluene;
at -78 - 20 ℃;
- Guidance literature:
-
(R)-1,2,3,4-tetrahydroquinaldine;
With
triethylamine; phosphorus trichloride;
In
toluene;
at 0 - 80 ℃;
Inert atmosphere;
(R)-1,1'-Bi-2-naphthol;
With
triethylamine;
In
tetrahydrofuran; toluene;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ja210923k
