C₂₃H₃₀O₃

Base Information

• Chemical Name: C₂₃H₃₀O₃
• CAS No.: 1313396-45-0
• Molecular Formula: C₂₃H₃₀O₃
• Molecular Weight: 354.489
• Mol file: 1313396-45-0.mol

Synonyms:

Chemical Property of C₂₃H₃₀O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₀O₃

There total 28 articles about C₂₃H₃₀O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H32O4 (1313396-44-9) → C23H30O3 (1313396-45-0)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In dichloromethane; at 25 ℃; for 2h; Inert atmosphere;

DOI:10.1002/asia.201100805

Reference yield:

C12H18O (1313396-30-3) → C23H30O3 (1313396-45-0)

Guidance literature:

Multi-step reaction with 14 steps

1.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran; toluene / 20 h / -78 - 40 °C / Inert atmosphere

1.2: 0 °C / Inert atmosphere

2.1: 1H-imidazole; dmap / N,N-dimethyl-formamide / 48 h / 40 °C / Inert atmosphere

3.1: di(rhodium)tetracarbonyl dichloride / toluene / 50 h / 90 °C / 760.05 Torr

4.1: 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride / dichloromethane / 12 h / 25 °C / Inert atmosphere

4.2: -10 - 20 °C / Inert atmosphere

5.1: 3-chloro-benzenecarboperoxoic acid / ethyl acetate / 2 h / 0 °C / Inert atmosphere

6.1: 2,2,6,6-tetramethyl-piperidine; n-butyllithium; dimethylaluminum chloride / hexane; n-heptane; benzene / 2 h / 0 °C / Inert atmosphere

6.2: Inert atmosphere

7.1: sodium hydride / N,N-dimethyl-formamide / 0.83 h / 50 °C / Inert atmosphere

7.2: 5 h / 50 °C / Inert atmosphere

8.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 21 h / 40 °C / Inert atmosphere

9.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 1.5 h / 25 °C / Inert atmosphere

10.1: diisobutylaluminium hydride / hexane; dichloromethane / 2 h / -78 °C / Inert atmosphere

10.2: 0 °C / Inert atmosphere

11.1: pyridine; dmap / tetrahydrofuran; benzene / 3 h / 30 °C / Inert atmosphere

11.2: 16 h / 30 °C / Inert atmosphere

12.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / 3.5 h / 90 °C / Reflux; Inert atmosphere

13.1: diisobutylaluminium hydride / hexane; dichloromethane / 3 h / -78 °C / Inert atmosphere

13.2: Inert atmosphere

14.1: triethylamine / dichloromethane / 2 h / 25 °C / Inert atmosphere

With pyridine; 2,2,6,6-tetramethyl-piperidine; 1H-imidazole; dmap; n-butyllithium; 2,6-di-tert-butyl-4-methylpyridine; di(rhodium)tetracarbonyl dichloride; 2,2'-azobis(isobutyronitrile); trifluoromethylsulfonic anhydride; tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; dimethylaluminum chloride; sodium hydride; diisobutylaluminium hydride; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; hexane; n-heptane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1039/c1cc11005e

Reference yield:

2,2-dimethyl-4-pentenal (5497-67-6) → C23H30O3 (1313396-45-0)

Guidance literature:

Multi-step reaction with 15 steps

1.1: (1R,2R)-3-tert-butyldimethylsilyloxy-2-(N,N-dimethylamino)-1-p-nitrophenyl-1-propanol; zinc trifluoromethanesulfonate; triethylamine / toluene / 0.5 h / 55 °C / Inert atmosphere

1.2: 46 h / 55 °C / Inert atmosphere

2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran; toluene / 20 h / -78 - 40 °C / Inert atmosphere

2.2: 0 °C / Inert atmosphere

3.1: 1H-imidazole; dmap / N,N-dimethyl-formamide / 48 h / 40 °C / Inert atmosphere

4.1: di(rhodium)tetracarbonyl dichloride / toluene / 50 h / 90 °C / 760.05 Torr

5.1: 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride / dichloromethane / 12 h / 25 °C / Inert atmosphere

5.2: -10 - 20 °C / Inert atmosphere

6.1: 3-chloro-benzenecarboperoxoic acid / ethyl acetate / 2 h / 0 °C / Inert atmosphere

7.1: 2,2,6,6-tetramethyl-piperidine; n-butyllithium; dimethylaluminum chloride / hexane; n-heptane; benzene / 2 h / 0 °C / Inert atmosphere

7.2: Inert atmosphere

8.1: sodium hydride / N,N-dimethyl-formamide / 0.83 h / 50 °C / Inert atmosphere

8.2: 5 h / 50 °C / Inert atmosphere

9.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 21 h / 40 °C / Inert atmosphere

10.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 1.5 h / 25 °C / Inert atmosphere

11.1: diisobutylaluminium hydride / hexane; dichloromethane / 2 h / -78 °C / Inert atmosphere

11.2: 0 °C / Inert atmosphere

12.1: pyridine; dmap / tetrahydrofuran; benzene / 3 h / 30 °C / Inert atmosphere

12.2: 16 h / 30 °C / Inert atmosphere

13.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / 3.5 h / 90 °C / Reflux; Inert atmosphere

14.1: diisobutylaluminium hydride / hexane; dichloromethane / 3 h / -78 °C / Inert atmosphere

14.2: Inert atmosphere

15.1: triethylamine / dichloromethane / 2 h / 25 °C / Inert atmosphere

With pyridine; 2,2,6,6-tetramethyl-piperidine; 1H-imidazole; dmap; n-butyllithium; 2,6-di-tert-butyl-4-methylpyridine; di(rhodium)tetracarbonyl dichloride; (1R,2R)-3-tert-butyldimethylsilyloxy-2-(N,N-dimethylamino)-1-p-nitrophenyl-1-propanol; 2,2'-azobis(isobutyronitrile); trifluoromethylsulfonic anhydride; tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; dimethylaluminum chloride; zinc trifluoromethanesulfonate; sodium hydride; diisobutylaluminium hydride; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; hexane; n-heptane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1039/c1cc11005e

upstream raw materials:

C₁₉H₃₄O₂Si

C₂₀H₃₆OSi

C₂₀H₃₆O₂Si

C₂₀H₃₆O₂Si