(4'-Dimethylaminophenyl)-10,10'-di(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydrobenzindolo<2,3-a>chinolizinyl)methan

Base Information

• Chemical Name: (4'-Dimethylaminophenyl)-10,10'-di(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydrobenzindolo<2,3-a>chinolizinyl)methan
• CAS No.: 78286-94-9
• Molecular Formula: C₅₁H₆₁N₅O₆
• Molecular Weight: 840.075
• Mol file: 78286-94-9.mol

Synonyms:

Chemical Property of (4'-Dimethylaminophenyl)-10,10'-di(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydrobenzindolo<2,3-a>chinolizinyl)methan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4'-Dimethylaminophenyl)-10,10'-di(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydrobenzindolo<2,3-a>chinolizinyl)methan

There total 1 articles about (4'-Dimethylaminophenyl)-10,10'-di(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydrobenzindolo<2,3-a>chinolizinyl)methan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-dimethylamino-benzaldehyde (100-10-7) + Yohimbine (146-48-5) → 10-(4'-Dimethylaminophenyl-1'-methinmethoxy)-(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4α,5,7,8,13,13b,14,14α-dodecahydrobenzindolo<2,3-a>chinolizin) (78286-93-8) + 11-(4'-Dimethylaminophenyl-1'-methinmethoxy)-(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4α,5,7,8,13,13b,14,14α-dodecahydrobenzindolo<2,3-a>chinolizin) (78412-84-7) + 9-(4'-Dimethylaminophenyl-1'-methinmethoxy)-(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4α,5,7,8,13,13b,14,14α-dodecahydrobenzindolo<2,3-a>chinolizin) + (4'-Dimethylaminophenyl)-10,10'-di(16α,17α)-16-methoxycarbonyl-17-hydroxy-(<4aR-(4aα,13bβ,14aβ)>-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydrobenzindolo<2,3-a>chinolizinyl)methan (78286-94-9)

Guidance literature:

hydrogenchloride; In methanol; at 0 ℃; for 2h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1002/ardp.19813140209

upstream raw materials:

4-dimethylamino-benzaldehyde

Yohimbine