pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether

Base Information

• Chemical Name: pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether
• CAS No.: 124551-23-1
• Molecular Formula: C₂₂H₃₂O₁₂P₂
• Molecular Weight: 550.436
• Mol file: 124551-23-1.mol

Synonyms:

Chemical Property of pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether

There total 6 articles about pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,14-bis{2-[(hydroxy)(ethoxy)phosphoryl]phenoxy}-3,6,9,12-tetraoxatetradecane (124551-17-3) → pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether (124551-23-1)

Guidance literature:

With chloro-trimethyl-silane; tetrabutylammomium bromide; sodium bromide; In acetonitrile; for 5h; Yield given;

Reference yield:

O-methoxymethylphenol (824-91-9) → pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether (124551-23-1)

Guidance literature:

Multi-step reaction with 6 steps

1: 1) BuLi / 1) hexane, 2) THF, -60 deg C, 2h

2: 95 percent / HCl / ethanol

3: 82 percent / 55percent NaH / diethyl ether; hexane

4: 64 percent / dioxane / 15 h / 80 °C

5: NaOH / aq. ethanol / 15 h / Heating

6: NaBr, Bu₄N+Br-, Me₃SiCl / acetonitrile / 5 h

With hydrogenchloride; sodium hydroxide; n-butyllithium; chloro-trimethyl-silane; tetrabutylammomium bromide; sodium hydride; sodium bromide; In 1,4-dioxane; diethyl ether; ethanol; hexane; acetonitrile;

Reference yield:

(2-hydroxy-phenyl)-phosphonic acid diethyl ester (69646-14-6) → pentaethylene glycol bis(o-dihydroxyphosphinylphenyl) ether (124551-23-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 82 percent / 55percent NaH / diethyl ether; hexane

2: 64 percent / dioxane / 15 h / 80 °C

3: NaOH / aq. ethanol / 15 h / Heating

4: NaBr, Bu₄N+Br-, Me₃SiCl / acetonitrile / 5 h

With sodium hydroxide; chloro-trimethyl-silane; tetrabutylammomium bromide; sodium hydride; sodium bromide; In 1,4-dioxane; diethyl ether; ethanol; hexane; acetonitrile;

upstream raw materials:

1,14-bis{2-[(hydroxy)(ethoxy)phosphoryl]phenoxy}-3,6,9,12-tetraoxatetradecane

O-methoxymethylphenol

(2-hydroxy-phenyl)-phosphonic acid diethyl ester

2-(methoxymethoxy)phenylphosphonic acid diethyl ester