2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol

Base Information

• Chemical Name: 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol
• CAS No.: 220277-45-2
• Molecular Formula: C₄₉H₆₉BrO₁₄Si₂
• Molecular Weight: 1018.15

Synonyms:

Chemical Property of 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol

There total 1 articles about 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + 4-deoxy-4-C-<(trimethylgermyl)ethynyl>-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol → 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol (220277-45-2)

Guidance literature:

With pyridine; N-Bromosuccinimide; copper(I) bromide; Yield given; Multistep reaction; 1.) CH₂Cl₂, 12 h; 2.) acetone, RT, 2 h;

DOI:10.1002/(SICI)1522-2675(19981216)81:12<2157::AID-HLCA2157>3.0.CO;2-4

Reference yield: 2.0%

4-deoxy-4-C-<(trimethylgermyl)ethynyl>-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol + 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol (220277-45-2) → 4-deoxy-4-C-<4-<2,3,6-tri-O-acetyl-β-D-glucopyranose-1,4-diyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol-6-yl>buta-1,3-diyne-1-yl>-β-D-glucopyranosyl-...

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(l) iodide; P(furyl)3; triethylamine; In dimethyl sulfoxide; for 17h; Ambient temperature;

DOI:10.1002/(SICI)1522-2675(19981216)81:12<2157::AID-HLCA2157>3.0.CO;2-4

Reference yield:

2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol (220277-45-2) + 4-deoxy-4-C-<(trimethylgermyl)ethynyl>-β-D-glucopyranosyl-(1->8)-5,9-anhydro-1,2,3,4-tetradeoxy-6,7-bis-O-(4-methoxybenzyl)-10-O-(thexyldimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol-1-yl(1->4-C)-2,3,6-tri-O-acetyl-4-deoxy-β-D-glucopyranosyl-... → 4-deoxy-4-C-<4-<2,3,6-tri-O-acetyl-β-D-glucopyranose-1,4-diyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol-6-yl>buta-1,3-diyne-1-yl>-β-D-glucopyranosyl-...

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(l) iodide; P(furyl)3; triethylamine; In dimethyl sulfoxide; for 48h; Ambient temperature;

DOI:10.1002/(SICI)1522-2675(19981216)81:12<2157::AID-HLCA2157>3.0.CO;2-4

upstream raw materials:

acetic anhydride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220277-45-2 2,3,6-tri-O-acetyl-4-C-(bromoethynyl)-4-deoxy-β-D-glucopyranosyl-(1->6)-3,7-anhydro-1,2-dideoxy-4,5-bis-O-(4-methoxybenzyl)-8-O-(thexyldimethylsilyl)-1-C-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol

Send

Send

Metric Ton KG G Pound L ML

Send

Send