2,2-dimethyl-4-oxo-4-phenylbutanal

Base Information

• Chemical Name: 2,2-dimethyl-4-oxo-4-phenylbutanal
• CAS No.: 128260-00-4
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• Mol file: 128260-00-4.mol

Synonyms:

Chemical Property of 2,2-dimethyl-4-oxo-4-phenylbutanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-dimethyl-4-oxo-4-phenylbutanal

There total 3 articles about 2,2-dimethyl-4-oxo-4-phenylbutanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methyl-1-phenyl-but-2-en-1-one (5650-07-7) → 2,2-dimethyl-4-oxo-4-phenylbutanal (128260-00-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / sodium ethoxide / ethanol / 36 h / 80 °C

2: 1) KOH, 2) potassium permanganate, magnesium sulphate / 1) methanol, 25 deg C, 2h, 2) water, 1h, pH= 7

With potassium hydroxide; potassium permanganate; sodium ethanolate; magnesium sulfate; In ethanol;

Reference yield:

4,4-ethylenedioxy-2-methyl-4-phenylbutan-2-ol (128260-03-7) → 2,2-dimethyl-4-oxo-4-phenylbutanal (128260-00-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 55 percent / HCl / H₂O; acetone / 5 h / Heating

2: 60 percent / sodium ethoxide / ethanol / 36 h / 80 °C

3: 1) KOH, 2) potassium permanganate, magnesium sulphate / 1) methanol, 25 deg C, 2h, 2) water, 1h, pH= 7

With hydrogenchloride; potassium hydroxide; potassium permanganate; sodium ethanolate; magnesium sulfate; In ethanol; water; acetone;

Reference yield:

3,3-dimethyl-4-nitro-1-phenyl-butan-1-one (128259-94-9) → 2,2-dimethyl-4-oxo-4-phenylbutanal (128260-00-4)

Guidance literature:

With potassium hydroxide; potassium permanganate; magnesium sulfate; Yield given. Multistep reaction; 1) methanol, 25 deg C, 2h, 2) water, 1h, pH= 7;

upstream raw materials:

3,3-dimethyl-4-nitro-1-phenyl-butan-1-one

3-methyl-1-phenyl-but-2-en-1-one

4,4-ethylenedioxy-2-methyl-4-phenylbutan-2-ol

Downstream raw materials:

2-hydroxy-3,3-dimethyl-5-phenyl-3,4-dihydro-2H-pyrrole

2, 3-dimethyl-5-phenyl-1H-pyrrole

3,3-dimethyl-5-phenyl-3H-pyrrole