5,7-Dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline

Base Information

Chemical Name:5,7-Dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline
CAS No.:129633-26-7
Molecular Formula:C₁₈H₁₄F₃NO₂
Molecular Weight:333.31
Hs Code.:
European Community (EC) Number:662-241-3

Synonyms:5,7-dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline;129633-26-7;AKOS017343636

Suppliers and Price of 5,7-Dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5,7-Dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:333.09766318
Heavy Atom Count:24
Complexity:412

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C(=CC(=N2)C3=CC=CC=C3)C(F)(F)F)C(=C1)OC

Technology Process of 5,7-Dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline

There total 3 articles about 5,7-Dimethoxy-2-phenyl-4-(trifluoromethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 129633-19-8
(Z)-4-(3,5-Dimethoxy-phenylamino)-1,1,1-trifluoro-4-phenyl-but-3-en-2-one

: 129633-26-7
5,7-Dimethoxy-2-phenyl-4-trifluoromethyl-quinoline

Guidance literature:: With trifluoroacetic acid; for 0.5h; Heating;
DOI:10.1016/S0040-4039(00)94673-2

Reference yield:

: 58518-08-4
1,1,1-trifluoro-4-phenylbut-3-yn-2-one

: 129633-26-7
5,7-Dimethoxy-2-phenyl-4-trifluoromethyl-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / methanol / Ambient temperature

2: 93 percent / CF₃CO₂H / 0.5 h / Heating

With trifluoroacetic acid; In methanol;
DOI:10.1016/S0040-4039(00)94673-2

Reference yield:

: 10272-07-8
3.5-dimethoxyaniline

: 129633-26-7
5,7-Dimethoxy-2-phenyl-4-trifluoromethyl-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / methanol / Ambient temperature

2: 93 percent / CF₃CO₂H / 0.5 h / Heating

With trifluoroacetic acid; In methanol;
DOI:10.1016/S0040-4039(00)94673-2