1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

Base Information

Chemical Name:1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃
CAS No.:874635-39-9
Molecular Formula:C₃₇H₆₂N₂O₅
Molecular Weight:614.91
Hs Code.:

1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D<sub>3</sub>

Synonyms:

Suppliers and Price of 1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

There total 14 articles about 1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 874635-37-7
1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-6,7-didehydro-3-deoxyprevitamin D₃

: 874635-39-9
1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

Guidance literature:: With quinoline; Lindlar's catalyst; hydrogen; In methanol; hexane; at 20 ℃; for 0.333333h;
DOI:10.1016/j.bmc.2005.09.009

Reference yield:

: 169437-98-3
(3R,5S)-5-acetoxy-1-ethynyl-3-hydroxy-2-methylcyclohex-1-ene

: 874635-39-9
1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

Guidance literature:: Multi-step reaction with 9 steps

1: 82 percent / Ph₃P; diethylazodicarboxylate / tetrahydrofuran / 4 h / 20 °C

2: methylamine / ethanol / 36 h / 20 - 65 °C

3: NaHCO₃ / H₂O; CHCl₃ / 24 h / 20 °C

4: 94 percent / triethyamine / CH₂Cl₂ / 3 h / 0 °C

5: 79 percent / NaN₃ / dimethylformamide / 6 h / 65 °C

6: 82 percent / NaOH; Me₃P / H₂O; dimethylformamide / 24 h / 20 °C

7: CuI; Pd(PPh₃)2(OAc)2; diethylamine / dimethylformamide / 1 h / 20 °C

8: tetrabutylammonium fluoride / tetrahydrofuran / 12 h / 20 °C

9: H₂; quinoline; Lindlar catalyst / methanol; hexane / 0.33 h / 20 °C

With quinoline; sodium hydroxide; Lindlar's catalyst; copper(l) iodide; sodium azide; bis(triphenylphosphine) palladium (Il) acetate; tetrabutyl ammonium fluoride; hydrogen; sodium hydrogencarbonate; diethylamine; triethylamine; triphenylphosphine; methylamine; diethylazodicarboxylate; trimethylphosphane; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; chloroform; water; N,N-dimethyl-formamide; 1: Mitsunobu reaction / 6: Staudinger reaction;
DOI:10.1016/j.bmc.2005.09.009

Reference yield:

: 874635-26-4
(3S,5S)-5-acetoxy-1-ethynyl-2-methyl-3-phthalimidocyclohex-1-ene

: 874635-39-9
1α,3β-bis[(tert-butoxycarbonyl)amino]-25-hydroxy-3-deoxyprevitamin D₃

Guidance literature:: Multi-step reaction with 8 steps

1: methylamine / ethanol / 36 h / 20 - 65 °C

2: NaHCO₃ / H₂O; CHCl₃ / 24 h / 20 °C

3: 94 percent / triethyamine / CH₂Cl₂ / 3 h / 0 °C

4: 79 percent / NaN₃ / dimethylformamide / 6 h / 65 °C

5: 82 percent / NaOH; Me₃P / H₂O; dimethylformamide / 24 h / 20 °C

6: CuI; Pd(PPh₃)2(OAc)2; diethylamine / dimethylformamide / 1 h / 20 °C

7: tetrabutylammonium fluoride / tetrahydrofuran / 12 h / 20 °C

8: H₂; quinoline; Lindlar catalyst / methanol; hexane / 0.33 h / 20 °C

With quinoline; sodium hydroxide; Lindlar's catalyst; copper(l) iodide; sodium azide; bis(triphenylphosphine) palladium (Il) acetate; tetrabutyl ammonium fluoride; hydrogen; sodium hydrogencarbonate; diethylamine; triethylamine; methylamine; trimethylphosphane; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; chloroform; water; N,N-dimethyl-formamide; 5: Staudinger reaction;
DOI:10.1016/j.bmc.2005.09.009