2,3,4,4a,5,6,7,8-Octahydro-quinoline

Base Information

• Chemical Name: 2,3,4,4a,5,6,7,8-Octahydro-quinoline
• CAS No.: 1074-06-2
• Molecular Formula: C9H15N
• Molecular Weight: 137.225
• DSSTox Substance ID: DTXSID90449505
• Mol file: 1074-06-2.mol

Synonyms:1074-06-2;2,3,4,4a,5,6,7,8-octahydroquinoline;2,3,4,4a,5,6,7,8-octahydro-quinoline;quinoline, 2,3,4,4a,5,6,7,8-octahydro-;SCHEMBL4613968;DTXSID90449505

Chemical Property of 2,3,4,4a,5,6,7,8-Octahydro-quinoline

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 137.120449483
• Heavy Atom Count: 10
• Complexity: 149

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2=NCCCC2C1

Technology Process of 2,3,4,4a,5,6,7,8-Octahydro-quinoline

There total 1 articles about 2,3,4,4a,5,6,7,8-Octahydro-quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Ethoxy-2,3,4,4a,5,6,7,8-octahydrochinolinium-tetrafluoroborat → Δ1(8a)-octahydroquinoline (1074-06-2) + acetaldehyde (75-07-0,9002-91-9)

Guidance literature:

With hydrogenchloride; trimethylamine; Yield given. Multistep reaction; 1) chloroform, -65 dec C, 1 min.; 2) 0 dec C;

Reference yield: 88.0%

Δ1(8a)-octahydroquinoline (1074-06-2) + diphenylcyclopropenone (886-38-4) → 5,6-Tetramethylen-2,3-diphenyl-1-azabicyclo<4.3.0>non-2-en-4-on (108201-21-4)

Guidance literature:

In toluene; for 1h; Heating;

DOI:10.1055/s-1986-31820

Reference yield: 86.0%

Δ1(8a)-octahydroquinoline (1074-06-2) → trans-decahydroquinoline (767-92-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h;

DOI:10.1016/0040-4020(82)80182-8

Downstream raw materials:

4-Dicyanomethylen-5,6-tetramethylen-2,3-diphenyl-1-azabicyclo<4.3.0>non-2-en

2-Cyanophenylmethylen-1,1a-diphenyl-1,2,5,6,6a,7,8,9a,9b-decahydro-1,9a-cyclopropa-4H-pyrrolo<3.2.1-ij>-chinolin

(4aR,8R,SR)-8-(p-tolylsulfinyl)-2,3,4,4a,5,6,7,8-octahydro-4a-quinolinol

(4aS,8S)-8-((R)-Toluene-4-sulfinyl)-3,4,5,6,7,8-hexahydro-2H-quinolin-4a-ol