3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene

Base Information

• Chemical Name: 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene
• CAS No.: 1616593-38-4
• Molecular Formula: C₂₆H₃₈Cl₂N₂O₂
• Molecular Weight: 481.506
• Mol file: 1616593-38-4.mol

Synonyms:

Chemical Property of 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene

There total 5 articles about 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C26H42Cl2N2O4 (1642301-69-6) → 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene (1616593-38-4)

Guidance literature:

With triethylamine; trichlorophosphate; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ja504808r

Reference yield:

8-chlorooctan-1-ol (23144-52-7) → 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene (1616593-38-4)

Guidance literature:

Multi-step reaction with 6 steps

1: phosphorus tribromide / 6 h / 0 - 20 °C / Inert atmosphere

2: potassium hydroxide / dimethyl sulfoxide / 3 h / 20 °C / Inert atmosphere

3: acetic acid; nitric acid / water / 1 h / 0 °C / Inert atmosphere

4: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / Inert atmosphere

5: dichloromethane / 3 h / 0 °C / Inert atmosphere

6: triethylamine; trichlorophosphate / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; nitric acid; phosphorus tribromide; acetic acid; triethylamine; potassium hydroxide; trichlorophosphate; In ethanol; dichloromethane; water; dimethyl sulfoxide;

DOI:10.1021/ja504808r

Reference yield:

3,6-dimethyl-1,2-di(8-chlorooctoxy)benzene (1616593-44-2) → 3,6-dimethyl-4,5-di(8-chlorooctoxy)-1,2-diisocyanobenzene (1616593-38-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / Inert atmosphere

2: dichloromethane / 3 h / 0 °C / Inert atmosphere

3: triethylamine; trichlorophosphate / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; triethylamine; trichlorophosphate; In ethanol; dichloromethane;

DOI:10.1021/ja504808r

upstream raw materials:

8-chlorooctan-1-ol

1-bromo-8-chloro-octane

3,6-dimethyl-1,2-di(8-chlorooctoxy)benzene

3,6-dimethyl-1,2-di(8-chlorooctoxy)benzene