Technology Process of C19H22N4O2
There total 7 articles about C19H22N4O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C24H32N4O5;
With
trifluoroacetic acid;
In
dichloromethane;
for 12h;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
dichloromethane;
for 24h;
DOI:10.1002/chir.22160
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium cyanoborohydride / ethanol / 0.5 h
2.1: sodium cyanoborohydride / ethanol / 0.5 h
3.1: thionyl chloride / dichloromethane / 5 h / -10 - 25 °C
4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h
5.1: sodium hydroxide / acetonitrile / 3 h / 20 °C
6.1: trifluoroacetic acid / dichloromethane / 12 h
6.2: 24 h
With
thionyl chloride; sodium cyanoborohydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; sodium hydroxide;
In
ethanol; dichloromethane; acetonitrile;
DOI:10.1002/chir.22160
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h
2.1: sodium hydroxide / acetonitrile / 3 h / 20 °C
3.1: trifluoroacetic acid / dichloromethane / 12 h
3.2: 24 h
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; sodium hydroxide;
In
dichloromethane; acetonitrile;
DOI:10.1002/chir.22160
