4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl-
CAS No.:108238-51-3
Molecular Formula:C15H10O5
Molecular Weight:270.241
Hs Code.:
DSSTox Substance ID:DTXSID30441169
Nikkaji Number:J1.278.444I
Wikidata:Q82257805
Mol file:108238-51-3.mol

Synonyms:4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl-;108238-51-3;3,7,8-Trihydroxy-2-phenyl-4H-chromen-4-one;7,8-Dihydroxyflavonol;3,7,8-trihydroxyflavone;3,7,8-TRIHYDROXY-2-PHENYLCHROMEN-4-ONE;SCHEMBL5569925;DTXSID30441169

Suppliers and Price of 4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl-

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:270.05282342
Heavy Atom Count:20
Complexity:424

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=O)C3=C(O2)C(=C(C=C3)O)O)O

Technology Process of 4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl-

There total 9 articles about 4H-1-Benzopyran-4-one, 3,7,8-trihydroxy-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 258856-70-1
2-phenyl-3,7,8-tribenzoyloxy-4-oxo-4H-1-benzopyran

: 108238-51-3
2-phenyl-3,7,8-trihydroxy-4-oxo-4H-1-benzopyran

Guidance literature:: With sodium hydroxide; water; In ethanol; at 60 ℃; for 2h;
DOI:10.1021/jo990735q

Reference yield:

: 528-21-2
2',3',4'-trihydroxyacetophenone

: 108238-51-3
2-phenyl-3,7,8-trihydroxy-4-oxo-4H-1-benzopyran

Guidance literature:: Multi-step reaction with 6 steps

1: 89 percent / pyridine / 2 h / 20 °C

2: 77 percent / phenyltrimethylammonium tribromide / tetrahydrofuran / 6 h / 20 °C

3: 73 percent / acetonitrile / 48 h / 20 °C

4: NaH / tetrahydrofuran / Heating

5: 451 mg / H₂SO₄ / acetic acid / 1.5 h / 60 °C

6: 91 percent / NaOH; H₂O / ethanol / 2 h / 60 °C

With pyridine; sodium hydroxide; sulfuric acid; water; phenyltrimethylammonium tribromide; sodium hydride; In tetrahydrofuran; ethanol; acetic acid; acetonitrile; 1: Acylation / 2: Bromination / 3: Substitution / 4: Rearrangement / 5: Cyclization / 6: Hydrolysis;
DOI:10.1021/jo990735q

Reference yield:

: 258856-58-5
2',3',4'-tribenzoyloxyacetophenone

: 108238-51-3
2-phenyl-3,7,8-trihydroxy-4-oxo-4H-1-benzopyran

Guidance literature:: Multi-step reaction with 5 steps

1: 77 percent / phenyltrimethylammonium tribromide / tetrahydrofuran / 6 h / 20 °C

2: 73 percent / acetonitrile / 48 h / 20 °C

3: NaH / tetrahydrofuran / Heating

4: 451 mg / H₂SO₄ / acetic acid / 1.5 h / 60 °C

5: 91 percent / NaOH; H₂O / ethanol / 2 h / 60 °C

With sodium hydroxide; sulfuric acid; water; phenyltrimethylammonium tribromide; sodium hydride; In tetrahydrofuran; ethanol; acetic acid; acetonitrile; 1: Bromination / 2: Substitution / 3: Rearrangement / 4: Cyclization / 5: Hydrolysis;
DOI:10.1021/jo990735q