Technology Process of ethyl 5-ethenylpyridine-2-carboxylate
There total 2 articles about ethyl 5-ethenylpyridine-2-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0);
In
N,N-dimethyl-formamide;
at 100 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.bmc.2015.05.036
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sulfuric acid / 2 h / 75 °C
2: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 2 h / 100 °C / Inert atmosphere
With
sulfuric acid;
tetrakis(triphenylphosphine) palladium(0);
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: palladium 10% on activated carbon; hydrogen / ethanol / 3 h / 20 °C
2: m-chloroperoxybenzoic acid / acetonitrile / 20 h / 20 °C
3: trifluoroacetic anhydride / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere
4: N-Bromosuccinimide / N,N-dimethyl-formamide / 1 h / 20 °C
5: silver carbonate / toluene / 2 h / 40 °C
With
N-Bromosuccinimide; m-chloroperoxybenzoic acid; palladium 10% on activated carbon; hydrogen; silver carbonate; trifluoroacetic anhydride;
In
ethanol; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1016/j.bmc.2015.05.036
