3-[4-(4-Nitrophenyl)piperazin-1-yl]propanoic acid

Base Information

Chemical Name:3-[4-(4-Nitrophenyl)piperazin-1-yl]propanoic acid
CAS No.:108911-74-6
Molecular Formula:C13H17N3O4
Molecular Weight:279.296
Hs Code.:
DSSTox Substance ID:DTXSID20586078
Mol file:108911-74-6.mol

Synonyms:108911-74-6;1-Piperazinepropanoic acid, 4-(4-nitrophenyl)-;3-[4-(4-nitrophenyl)piperazin-1-yl]propanoic acid;SCHEMBL2111232;DTXSID20586078;STL257360;AKOS002254673

Suppliers and Price of 3-[4-(4-Nitrophenyl)piperazin-1-yl]propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-[4-(4-Nitrophenyl)piperazin-1-yl]propanoic acid

Chemical Property:

XLogP3:-1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:279.12190603
Heavy Atom Count:20
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(=O)O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 3-[4-(4-Nitrophenyl)piperazin-1-yl]propanoic acid

There total 2 articles about 3-[4-(4-Nitrophenyl)piperazin-1-yl]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 539-74-2
Ethyl 3-bromopropionate

: 6269-89-2
1-(4-Nitrophenyl)piperazine

: 108911-74-6
3-[4-(4-nitrophenyl)-1-piperazinyl]propionic acid

Guidance literature:: With sodium hydrogencarbonate; In ethanol;

Reference yield:

: 454183-39-2
ethyl 3-[4-(4-nitrophenyl)-1-piperazinyl]propionate

: 108911-74-6
3-[4-(4-nitrophenyl)-1-piperazinyl]propionic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane;
DOI:10.1016/j.bmc.2007.11.049

Reference yield: 77.4%

: 7689-03-4,91926-09-9
camptothecin

: 108911-74-6
3-[4-(4-nitrophenyl)-1-piperazinyl]propionic acid

: 3-[4-(4-nitro-phenyl)-piperazin-1-yl]-propionic acid 4-ethyl-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-4-yl ester

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 7h;
DOI:10.1016/j.bmc.2004.04.023