2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans-

Base Information

Chemical Name:2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans-
CAS No.:116663-44-6
Molecular Formula:C₂₀H₂₅NO₅
Molecular Weight:359.422
Hs Code.:
DSSTox Substance ID:DTXSID701121133

Synonyms:DTXSID701121133;116663-44-6;2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans-

Suppliers and Price of 2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans-

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:359.17327290
Heavy Atom Count:26
Complexity:398

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=CC=C1)OC)OCCNCC2COC3=CC=CC=C3C2O
Isomeric SMILES:COC1=C(C(=CC=C1)OC)OCCNC[C@H]2COC3=CC=CC=C3[C@@H]2O

Technology Process of 2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans-

There total 3 articles about 2H-1-Benzopyran-4-ol, 3-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-3,4-dihydro-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 116635-68-8
3-<<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl>-4-chromanone

: 116663-44-6
tran<<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl>-4-chromanol

: 116635-70-2
cis-3-<<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl>-4-chromanol

Guidance literature:: With sodium tetrahydroborate; In methanol; for 6h; Ambient temperature;
DOI:10.1021/jm00120a009

Reference yield:

: 491-37-2
2,3-dihydro-4H-1-benzopyran-4-one

: 116663-44-6
tran<<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl>-4-chromanol

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / HCl / ethanol / 6 h / Heating

2: 40 percent / NaBH₄ / methanol / 6 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; In methanol; ethanol;
DOI:10.1021/jm00120a009

Reference yield:

: 87780-27-6
2-(2,6-dimethoxy-phenoxy)ethylamine hydrochloride

: 116663-44-6
tran<<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl>-4-chromanol

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / HCl / ethanol / 6 h / Heating

2: 40 percent / NaBH₄ / methanol / 6 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; In methanol; ethanol;
DOI:10.1021/jm00120a009