3-Amino-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide

Base Information

• Chemical Name: 3-Amino-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide
• CAS No.: 135832-45-0
• Molecular Formula: C₈H₁₂N₂O₅S₂
• Molecular Weight: 280.326
• ChEMBL ID: CHEMBL104524
• DSSTox Substance ID: DTXSID80872242
• Nikkaji Number: J459.527K
• Mol file: 135832-45-0.mol

Synonyms:CHEMBL104524;DTXSID80872242;BDBM50406450;135832-45-0;3-Amino-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide

Chemical Property of 3-Amino-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide

Chemical Property:

• XLogP3: -0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 280.01876383
• Heavy Atom Count: 17
• Complexity: 447

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)N)N)S(=O)(=O)CCO

Technology Process of 3-Amino-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide

There total 1 articles about 3-Amino-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-Hydroxy-ethanesulfonyl)-3-nitro-benzenesulfonamide (108966-79-6) → 3-Amino-4-(2-hydroxy-ethanesulfonyl)-benzenesulfonamide (135832-45-0)

Guidance literature:

With hydrogenchloride; iron; In ethanol; for 5h; Heating;

DOI:10.1021/jm00114a020

upstream raw materials:

4-(2-Hydroxy-ethanesulfonyl)-3-nitro-benzenesulfonamide