nonylmethylphenyl phosphine oxide

Base Information

• Chemical Name: nonylmethylphenyl phosphine oxide
• CAS No.: 1195517-31-7
• Molecular Formula: C₁₆H₂₇OP
• Molecular Weight: 266.364
• Mol file: 1195517-31-7.mol

Synonyms:

Chemical Property of nonylmethylphenyl phosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of nonylmethylphenyl phosphine oxide

There total 4 articles about nonylmethylphenyl phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylphosphonous acid dimethyl ester (2946-61-4) → nonylmethylphenyl phosphine oxide (1195517-31-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 18 h / Inert atmosphere; Reflux

2: phosphorus pentachloride / 1,2-dichloro-ethane / 40 °C / Inert atmosphere

3: Inert atmosphere

With phosphorus pentachloride; In 1,2-dichloro-ethane;

DOI:10.1021/ol202916j

Reference yield:

methyl methylphenylphosphinate (6389-79-3) → nonylmethylphenyl phosphine oxide (1195517-31-7)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus pentachloride / 1,2-dichloro-ethane / 40 °C / Inert atmosphere

2: Inert atmosphere

With phosphorus pentachloride; In 1,2-dichloro-ethane;

DOI:10.1021/ol202916j

Reference yield:

Dichlorophenylphosphine (644-97-3) → nonylmethylphenyl phosphine oxide (1195517-31-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: pyridine / hexane / 0.33 h / -10 °C / Inert atmosphere

1.2: 5.25 h / -10 - 20 °C / Inert atmosphere

2.1: 18 h / Inert atmosphere; Reflux

3.1: phosphorus pentachloride / 1,2-dichloro-ethane / 40 °C / Inert atmosphere

4.1: Inert atmosphere

With pyridine; phosphorus pentachloride; In hexane; 1,2-dichloro-ethane;

DOI:10.1021/ol202916j

upstream raw materials:

phenylphosphonous acid dimethyl ester

methyl methylphenylphosphinate

nonylmagnesium bromide

methyl(phenyl)phosphinic chloride