21-Acetoxy-11α,17α-dihydroxy-16β-methyl-pregna-1,4-dien-3.20-dion

Base Information

• Chemical Name: 21-Acetoxy-11α,17α-dihydroxy-16β-methyl-pregna-1,4-dien-3.20-dion
• CAS No.: 97274-92-5
• Molecular Formula: C₂₄H₃₂O₆
• Molecular Weight: 416.514
• Mol file: 97274-92-5.mol

Synonyms:

Chemical Property of 21-Acetoxy-11α,17α-dihydroxy-16β-methyl-pregna-1,4-dien-3.20-dion

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 21-Acetoxy-11α,17α-dihydroxy-16β-methyl-pregna-1,4-dien-3.20-dion

There total 6 articles about 21-Acetoxy-11α,17α-dihydroxy-16β-methyl-pregna-1,4-dien-3.20-dion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C24H31BrO6 → 16α-Methyl-1,4-pregnadien-11β,17α,21-triol-3,20-dion-21-acetat (5078-99-9,6242-16-6,13209-52-4,18769-24-9,97274-92-5,97334-37-7)

Guidance literature:

With chromium chloride hexahydrate; mercaptoacetic acid; zinc; In N,N-dimethyl acetamide; at -10 - 0 ℃; Solvent; Inert atmosphere; Industrial scale;

Reference yield:

→ 16β-Methylprednisolon-21-acetat (5078-99-9,6242-16-6,13209-52-4,18769-24-9,97274-92-5,97334-37-7)

Guidance literature:

16β-Methyl-prednisolon und Acetanhydrid in Py. <18 Stdn., 20grad>;

DOI:10.1021/ja01500a053

Reference yield:

→ 21-Acetoxy-11α,17α-dihydroxy-16β-methyl-pregna-1,4-dien-3.20-dion (5078-99-9,6242-16-6,13209-52-4,18769-24-9,97274-92-5,97334-37-7)

Guidance literature:

21-Acetoxy-2,4-dibrom-11α,17α-dihydroxy-16β-methyl-pregnan-3.20-dion, LiBr-Li2CO3 in Dimethylformamid;