3-(3,5-Dibromo-4-hydroxyphenyl)prop-2-enoic acid

Base Information

Chemical Name:3-(3,5-Dibromo-4-hydroxyphenyl)prop-2-enoic acid
CAS No.:119405-33-3
Molecular Formula:C₉H₆Br₂O₃
Molecular Weight:321.953
Hs Code.:
DSSTox Substance ID:DTXSID80694683
Mol file:119405-33-3.mol

Synonyms:3-(3,5-DIBROMO-4-HYDROXYPHENYL)PROP-2-ENOIC ACID;DTXSID80694683;FT-0771787

Suppliers and Price of 3-(3,5-Dibromo-4-hydroxyphenyl)prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3,5-dibromo-4-hydroxycinnamicacid 95
25g
$ 3245.00

Total 1 raw suppliers

Chemical Property of 3-(3,5-Dibromo-4-hydroxyphenyl)prop-2-enoic acid

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:321.86632
Heavy Atom Count:14
Complexity:230

Purity/Quality:: 3,5-dibromo-4-hydroxycinnamicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=C(C(=C1Br)O)Br)C=CC(=O)O

Technology Process of 3-(3,5-Dibromo-4-hydroxyphenyl)prop-2-enoic acid

There total 2 articles about 3-(3,5-Dibromo-4-hydroxyphenyl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141-82-2
malonic acid

: 2973-77-5
3,5-dibromo-4-hydroxybenzaldehyde

: 119405-33-3
3,5-dibromo-4-hydroxy cinnamic acid

Guidance literature:

Reference yield:

: 20407-70-9,119405-33-3
(Z)-3-(3,5-Dibromo-4-hydroxy-phenyl)-acrylic acid

Guidance literature:: /BRN= 417018/ / alkal. Lsg., Belichtung;

Reference yield:

: 119405-33-3
3,5-dibromo-4-hydroxy cinnamic acid

: (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-3-(3,5-dibromo-4-hydroxyphenyl)acrylamide

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice

With oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bmc.2016.02.017