C₃₃H₄₈N₂O₈

Base Information

• Chemical Name: C₃₃H₄₈N₂O₈
• CAS No.: 1381872-97-4
• Molecular Formula: C₃₃H₄₈N₂O₈
• Molecular Weight: 600.753
• Mol file: 1381872-97-4.mol

Synonyms:

Chemical Property of C₃₃H₄₈N₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₄₈N₂O₈

There total 7 articles about C₃₃H₄₈N₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C15H21NO3 (1381872-39-4) + Boc-L-phenylalaninal (72155-45-4) + butyric acid (107-92-6) → C33H48N2O8 (1381872-97-4)

Guidance literature:

In dichloromethane;

DOI:10.1016/j.tetlet.2012.04.018

Reference yield:

C15H23NO4 (1381872-71-4) → C33H48N2O8 (1381872-97-4)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrachloromethane; N-ethyl-N,N-diisopropylamine; triphenylphosphine / dichloromethane

2: dichloromethane

With tetrachloromethane; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In dichloromethane; 2: Passerini reaction;

DOI:10.1016/j.tetlet.2012.04.018

Reference yield:

BOC-O-benzyl-L-serine (23680-31-1) → C33H48N2O8 (1381872-97-4)

Guidance literature:

Multi-step reaction with 6 steps

1: potassium carbonate / acetone

2: lithium aluminium tetrahydride / tetrahydrofuran

3: sodium hydride / N,N-dimethyl-formamide

4: acetic anhydride; trifluoroacetic acid

5: tetrachloromethane; N-ethyl-N,N-diisopropylamine; triphenylphosphine / dichloromethane

6: dichloromethane

With tetrachloromethane; lithium aluminium tetrahydride; acetic anhydride; sodium hydride; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetone; 6: Passerini reaction;

DOI:10.1016/j.tetlet.2012.04.018

upstream raw materials:

C₁₉H₃₁NO₅

C₁₅H₂₃NO₄

C₁₅H₂₁NO₃

Boc-L-phenylalaninal

Downstream raw materials:

C₂₈H₄₀N₂O₆

Refernces