5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline

Base Information

Chemical Name:5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline
CAS No.:109722-74-9
Molecular Formula:C₁₆H₁₁NO
Molecular Weight:233.269
Hs Code.:
DSSTox Substance ID:DTXSID70435704
Nikkaji Number:J2.174.431J
Wikidata:Q82250781
ChEMBL ID:CHEMBL361500

Synonyms:109722-74-9;5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline;6,11-Dihydro-5H-indeno[1,2-c]isoquinolin-5-one;6,11-dihydroindeno[1,2-c]isoquinolin-5-one;CHEMBL361500;SCHEMBL2763222;BDBM27508;DTXSID70435704;MOPKKHSEOPGEBJ-UHFFFAOYSA-N;indeno[1,2-c]isoquinolinone, 1a;11H-Indeno[1,2-c]isoquinoline-5(6H)-one;5,6-dihydro-5-oxo-11h-indeno[1,2-c]isoquinoline;5,6-dihydro-5-oxo-11H-indeno [1,2-c] Isoquinoline;5H,6H,11H-INDENO[1,2-C]ISOQUINOLIN-5-ONE;9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaen-8-one

Suppliers and Price of 5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:233.084063974
Heavy Atom Count:18
Complexity:411

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=CC=CC=C2C3=C1C4=CC=CC=C4C(=O)N3

Technology Process of 5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline

There total 1 articles about 5,6-dihydro-5-oxo-11H-indeno [1,2-c]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 703-59-3
homophthalic anhydride

: 22115-41-9
2-(bromomethyl)benzonitrile

: 109722-74-9
5,6-dihydro-5-oxo-indeno[1,2-c]isoquinoline

: C₂₅H₁₆N₂O₃

: 5982-23-0
2-[(1-oxo-1H-isochromen-3-yl)methyl]benzoic acid

Guidance literature:: With triethylamine; In acetonitrile; for 15h; Heating;
DOI:10.1021/ol050331m

Reference yield:

: 109722-74-9
5,6-dihydro-5-oxo-indeno[1,2-c]isoquinoline

: 5-oxo-5,11-dihydro-6H-indeno[1,2-c]isoquinoline-9-sulfonic acid (3-phenyl-propyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / chlorosulfonyl chloride / 2 h / 20 °C

2: Et₃N / CH₂Cl₂ / 20 °C

With sulfuryl dichloride; triethylamine; In dichloromethane;
DOI:10.1021/jm0502891

Reference yield:

: 109722-74-9
5,6-dihydro-5-oxo-indeno[1,2-c]isoquinoline

: 501364-82-5
inotec indeno[1,2c]isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / chlorosulfonyl chloride / 2 h / 20 °C

2: 56 percent / Et₃N / CH₂Cl₂ / 24 h / 20 °C

With sulfuryl dichloride; triethylamine; In dichloromethane;
DOI:10.1021/jm0502891