perillyl phenyl sulfoxide

Base Information

• Chemical Name: perillyl phenyl sulfoxide
• CAS No.: 122346-04-7
• Molecular Formula: C₁₆H₂₀OS
• Molecular Weight: 260.4
• Mol file: 122346-04-7.mol

Synonyms:

Chemical Property of perillyl phenyl sulfoxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of perillyl phenyl sulfoxide

There total 2 articles about perillyl phenyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

benzenesulphinyl chloride (4972-29-6) + (5R)-2-methylene-5-(1-methylethenyl)-1-cyclohexanol (216655-61-7) → perillyl phenyl sulfoxide (122346-04-7,122346-07-0)

Guidance literature:

With triethylamine; In dichloromethane; at -78 ℃;

Reference yield:

(+)-limonene oxide (1195-92-2,4680-24-4,4959-35-7,6909-30-4,13837-75-7,32543-51-4,42477-94-1,66141-65-9,66141-66-0) → perillyl phenyl sulfoxide (122346-04-7,122346-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 87.5 percent / isopropylcyclohexylamine, n-butyllithium, methylmagnesium bromide / toluene; hexane; diethyl ether / 24 h / 0 °C

2: 61 percent / triethylamine / CH₂Cl₂ / -78 °C

With n-butyllithium; N-cyclohexylisopropylamine; methylmagnesium bromide; triethylamine; In diethyl ether; hexane; dichloromethane; toluene;

Reference yield:

perillyl phenyl sulfoxide (122346-04-7,122346-07-0) → L-perillaldehyde (5503-12-8) + [(R)-4-Isopropenyl-cyclohex-2-en-(E)-ylidenemethylsulfanyl]-benzene (122346-05-8,122346-06-9)

Guidance literature:

With 2,6-dimethylpyridine; trifluoroacetic anhydride; mercury dichloride; Yield given. Multistep reaction. Yields of byproduct given; 1.) acetonitrile, -40 deg C, 1 h, 2.) 25 deg C, 2 h;

upstream raw materials:

benzenesulphinyl chloride

(5R)-2-methylene-5-(1-methylethenyl)-1-cyclohexanol

(+)-limonene oxide

Downstream raw materials:

L-perillaldehyde

[(R)-4-Isopropenyl-cyclohex-2-en-(E)-ylidenemethylsulfanyl]-benzene