pyridoxatin

Base Information

• Chemical Name: pyridoxatin
• CAS No.: 135529-30-5
• Molecular Formula: C₁₅H₂₁NO₃
• Molecular Weight: 263.337
• Mol file: 135529-30-5.mol

Synonyms:2(1H)-Pyridinone,3-(2-ethenyl-4,6-dimethylcyclohexyl)-1,4-dihydroxy-, (1a,2b,4b,6b)-(-)-; (-)-Pyridoxatin;Acremonium BX 86 factor; BX 86; Pyridoxatin; Pyridoxatine

Chemical Property of pyridoxatin

Chemical Property:

• Vapor Pressure: 7.99E-08mmHg at 25°C
• Boiling Point: 393.5°Cat760mmHg
• Flash Point: 191.8°C
• PSA: 62.46000
• Density: 1.245g/cm³
• LogP: 2.74300

Purity/Quality:

98% ^*data from raw suppliers

Pyridoxatin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of pyridoxatin

There total 3 articles about pyridoxatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-maximiscin → pyridoxatin (135529-30-5)

Guidance literature:

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 75 ℃; for 24h;

Reference yield:

3-(2,4-Dimethyl-6-vinyl-cyclohexyl)-4-hydroxy-1-trimethylsilanyl-1H-pyridin-2-one → (+/-)-Pyridoxatin (135529-30-5)

Guidance literature:

With oxodiperoxymolybdenumpyridine hexamethylphosphoric triamide complex; ethylene diamine tetraacetic acid tetrasodium salt; Yield given. Multistep reaction; 1.) CH₂Cl₂, r.t., overnight, 2.) EtOAc, 4 h;

DOI:10.1021/jo00105a024

Reference yield:

3-(2-Ethenyl-4,6-dimethylcyclohexyl)-4-hydroxy-2(1H)-pyridinone → (+/-)-Pyridoxatin (135529-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1: TMSCl / 16 h / Heating

2: 1.) MoO₅*pyr*HMPA, 2.) aq. tetrasodium EDTA / 1.) CH₂Cl₂, r.t., overnight, 2.) EtOAc, 4 h

With chloro-trimethyl-silane; oxodiperoxymolybdenumpyridine hexamethylphosphoric triamide complex; ethylene diamine tetraacetic acid tetrasodium salt;

DOI:10.1021/jo00105a024

Refernces

• 1、 Snider, Barry B.,Lu, Qing. "Total Synthesis of (+/-)-Pyridoxatin". . p. 8065 - 8070. Retrieved 2007/10/02.