{ONO^Me,Cumyl}AlMe

Base Information

• Chemical Name: {ONO^Me,Cumyl}AlMe
• CAS No.: 1510836-95-9
• Molecular Formula: C₃₈H₃₈AlNO₂
• Molecular Weight: 567.707
• Mol file: 1510836-95-9.mol

Synonyms:

Chemical Property of {ONO^Me,Cumyl}AlMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {ONO^Me,Cumyl}AlMe

There total 4 articles about {ONO^Me,Cumyl}AlMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

C37H37NO2 (1510837-00-9) + trimethylaluminum (75-24-1) → {ONOMe,Cumyl}AlMe (1510836-95-9)

Guidance literature:

In n-heptane; toluene; at -78 - 80 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/om401047r

Reference yield:

4-methyl-2-(1-methyl-1-phenylethyl)phenol (2675-76-5) → {ONOMe,Cumyl}AlMe (1510836-95-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 4 h / 0 - 20 °C / Inert atmosphere

1.2: 18 h / Inert atmosphere

2.1: sec.-butyllithium / hexane; tetrahydrofuran / 0.33 h / -78 - 20 °C / Inert atmosphere

2.2: 0.5 h / -78 - 20 °C / Inert atmosphere

2.3: 72 h / 64 °C / Inert atmosphere

3.1: hydrogenchloride / ethanol; chloroform; water / 24 h / Reflux; Inert atmosphere

4.1: toluene; n-heptane / -78 - 80 °C / Inert atmosphere; Schlenk technique

With hydrogenchloride; sec.-butyllithium; sodium hydride; In tetrahydrofuran; ethanol; hexane; n-heptane; chloroform; water; N,N-dimethyl-formamide; toluene;

DOI:10.1021/om401047r

Reference yield:

1-(methoxymethyl)-4-methyl-2-(2-phenylpropan-2-yl)benzene → {ONOMe,Cumyl}AlMe (1510836-95-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sec.-butyllithium / hexane; tetrahydrofuran / 0.33 h / -78 - 20 °C / Inert atmosphere

1.2: 0.5 h / -78 - 20 °C / Inert atmosphere

1.3: 72 h / 64 °C / Inert atmosphere

2.1: hydrogenchloride / ethanol; chloroform; water / 24 h / Reflux; Inert atmosphere

3.1: toluene; n-heptane / -78 - 80 °C / Inert atmosphere; Schlenk technique

With hydrogenchloride; sec.-butyllithium; In tetrahydrofuran; ethanol; hexane; n-heptane; chloroform; water; toluene;

DOI:10.1021/om401047r

upstream raw materials:

C₃₇H₃₇NO₂

trimethylaluminum

4-methyl-2-(1-methyl-1-phenylethyl)phenol

C₄₁H₄₅NO₄

Downstream raw materials:

{ONO^Me,Cumyl}Al((rac)-OCH(CF₃)CH₂CO₂C₂H₅)