meta-TOPOLIN RIBOSIDE(mTR)

Base Information

• Chemical Name: meta-TOPOLIN RIBOSIDE(mTR)
• CAS No.: 110505-76-5
• Molecular Formula: C17H19N5O5
• Molecular Weight: 0.00000
• Mol file: 110505-76-5.mol

Synonyms:

Chemical Property of meta-TOPOLIN RIBOSIDE(mTR)

Chemical Property:

• Melting Point: 195.6-196.5℃ (water )
• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

meta-TopolinRiboside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: meta-Topolin Riboside can be used in biological study of auxin-cytokinin interaction and variations in their metabolic products during organogenesis, involving in regulation of E. autumnalis and E. zambesiaca shoot, root growth.

Technology Process of meta-TOPOLIN RIBOSIDE(mTR)

There total 4 articles about meta-TOPOLIN RIBOSIDE(mTR) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-hydroxybenzylamine (73604-31-6) + 6-Chloropurine riboside (2004-06-0) → 6-(3-hydroxybenzyl)adenosine (110505-76-5)

Guidance literature:

With triethylamine; In butan-1-ol; at -5 - 90 ℃;

DOI:10.3390/molecules18066990

Reference yield: 5.0%

9-(β-D-arabinofuranosyl)-9H-purin-6(1H)-one (7013-16-3) + 3-hydroxybenzylamine (73604-31-6) → 6-(3-hydroxybenzylamino)-9-β-D-arabinofuranosylpurine (110505-76-5)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 25 ℃; for 10h; Inert atmosphere;

Reference yield:

7-methylguanosine (22164-16-5) + m-topolin → 6-(3-hydroxybenzyl)adenosine (110505-76-5)

Guidance literature:

With dipotassium hydrogenphosphate; purine nucleotide phosphorylase; In ethanol; water; at 35 ℃; Enzymatic reaction;

DOI:10.1002/jlcr.3702

upstream raw materials:

3-hydroxybenzylamine

6-Chloropurine riboside

3-METHOXYBENZYLAMINE

7-methylguanosine

Refernces

• 1、 -. "6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF". Page/Page column 12-13. . Retrieved 2016/07/05.
• 2、 Chen, Jhih-Bin,Liu, Eric Minwei,Chern, Ting-Rong,Yang, Chieh-Wen,Lin, Chia-I,Huang, Nai-Kuei,Lin, Yun-Lian,Chern, Yijuang,Lin, Jung-Hsin,Fang, Jim-Min. "Design and Synthesis of Novel Dual-Action Compounds Targeting the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection". body text. p. 1390 - 1400. Retrieved 2012/06/30.