(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Base Information

Chemical Name:(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
CAS No.:58619-69-5
Molecular Formula:C₃₄H₃₄FN₃O₆S
Molecular Weight:631.725
Hs Code.:

(6<i>R</i>)-7<i>t</i>-((<i>R</i>)-2-<i>tert</i>-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6<i>r</i><i>H</i>)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Synonyms:

Suppliers and Price of (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

There total 3 articles about (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51762-49-3
(6R)-3-hydroxymethyl-8-oxo-7t-(2-phenyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c-carboxylic acid benzhydryl ester

: 58619-69-5
(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 2-chloro-1,1,2-trifluoro-triethylamine / CHCl₃

2: (i) MCPBA, (ii) PCl₃, DMF

3: PCl₅

With 2-chloro-1,1,2-trifluorotriethylamine; phosphorus pentachloride; In chloroform;
DOI:10.1002/hlca.19750580826

Reference yield:

: 58619-64-0
(6R)-3-fluoromethyl-8-oxo-7t-(2-phenyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c-carboxylic acid benzhydryl ester

: 58619-69-5
(6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-fluoromethyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Guidance literature:: Multi-step reaction with 3 steps

1: (i) MCPBA, (ii) PCl₃, DMF

2: PCl₅

With phosphorus pentachloride;
DOI:10.1002/hlca.19750580826