(+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

Base Information

Chemical Name:(+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione
CAS No.:78795-25-2
Molecular Formula:C₁₁H₁₆N₂O₃
Molecular Weight:224.26
Hs Code.:

(+/-)-1-<cis-3-(hydroxymethyl)cyclopentyl>-5-methyl-2,4(1H,3H)-pyrimidinedione

Synonyms:

Suppliers and Price of (+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

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Technology Process of (+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

There total 8 articles about (+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 78795-19-4
(+/-)-N-<aminocarbonyl>-3-methoxy-2-methyl-2-propenamide

: 78795-25-2,117957-63-8
(+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

Guidance literature:: With sulfuric acid; for 3.5h; Heating;

Reference yield:

: 78795-20-7,102099-18-3,117957-62-7,123288-54-0,1110772-11-6
(+/-)-cis-3-aminocyclopentanemethanol

: 78795-25-2,117957-63-8
(+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / dimethylformamide; benzene / Ambient temperature

2: 82 percent / 2N H₂SO₄ / 1.08 h / 100 °C

With sulfuric acid; In N,N-dimethyl-formamide; benzene;
DOI:10.1139/v88-009

Reference yield:

: 6054-16-6
cis-1,3-cyclopentanedicarboxylic acid anhydride

: 78795-25-2,117957-63-8
(+/-)-1--5-methyl-2,4(1H,3H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) r.t., 19 h; 2.) 2 deg C, 12 days

2: 26.2 g / thionyl chloride, pyridine, DMF / benzene / 2 h / Heating

3: 16.01 g / NH₃ / benzene / 0.5 h

4: 85.7 percent / lithium borohydride / tetrahydrofuran / 2 h / Heating

5: 74 percent / Ba(OH)2*8H₂O, bromine / H₂O / 1.) r.t., 2 h; 2.) 50-65 deg C, 1.25 h

6: 71 percent / dimethylformamide; benzene / Ambient temperature

7: 82 percent / 2N H₂SO₄ / 1.08 h / 100 °C

With pyridine; barium dihydroxide; lithium borohydride; thionyl chloride; sulfuric acid; ammonia; bromine; N,N-dimethyl-formamide; In tetrahydrofuran; water; N,N-dimethyl-formamide; benzene;
DOI:10.1139/v88-009