C₂₃H₂₈O₃

Base Information

• Chemical Name: C₂₃H₂₈O₃
• CAS No.: 115859-39-7
• Molecular Formula: C₂₃H₂₈O₃
• Molecular Weight: 352.474
• Mol file: 115859-39-7.mol

Synonyms:

Chemical Property of C₂₃H₂₈O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₈O₃

There total 8 articles about C₂₃H₂₈O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[2-((1R,2S,3R,5S)-3,5-Bis-benzyloxy-2-methoxymethyl-cyclopentyl)-ethylselanyl]-2-nitro-benzene → C23H28O3 (115859-39-7)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; for 2h;

DOI:10.1021/jo00254a020

Reference yield:

(3aα,4α,5β,6aα)-(-)-hexahydro-4-(methoxymethyl)-5-<(4-phenylphenyl)carboxy>-2H-cyclopentafuran-2-one (38361-00-1) → C23H28O3 (115859-39-7)

Guidance literature:

Multi-step reaction with 6 steps

1: 40 percent / LAH / tetrahydrofuran / 1 h / 5 - 25 °C

2: 4-(dimethylamino)pyridine, pyridine / 96 h / Ambient temperature

3: NaH / dimethylformamide / 1.5 h / 0 °C

4: 73 percent / aq. CH₃COOH / Ambient temperature

5: pyridine, tri-n-butylphosphine / 90 h / Ambient temperature

6: 30percent H₂O₂ / tetrahydrofuran / 2 h

With pyridine; dmap; lithium aluminium tetrahydride; tributylphosphine; dihydrogen peroxide; sodium hydride; acetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/jo00254a020

Reference yield:

(-)-Corey lactone 5-(4-phenylbenzoate) (31752-99-5) → C23H28O3 (115859-39-7)

Guidance literature:

Multi-step reaction with 7 steps

1: 36 percent / NaH / dimethylformamide / 0.5 h / 0 °C

2: 40 percent / LAH / tetrahydrofuran / 1 h / 5 - 25 °C

3: 4-(dimethylamino)pyridine, pyridine / 96 h / Ambient temperature

4: NaH / dimethylformamide / 1.5 h / 0 °C

5: 73 percent / aq. CH₃COOH / Ambient temperature

6: pyridine, tri-n-butylphosphine / 90 h / Ambient temperature

7: 30percent H₂O₂ / tetrahydrofuran / 2 h

With pyridine; dmap; lithium aluminium tetrahydride; tributylphosphine; dihydrogen peroxide; sodium hydride; acetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/jo00254a020

upstream raw materials:

(-)-Corey lactone 5-(4-phenylbenzoate)

(3aα,4α,5β,6aα)-(-)-hexahydro-4-(methoxymethyl)-5-<(4-phenylphenyl)carboxy>-2H-cyclopentafuran-2-one

benzyl bromide

<1S-(1α,2α,3β,4α)>-4-hydroxy-2-(hydroxyethyl)-3-(methoxymethyl)cyclopentanol

Downstream raw materials:

<1S-(1α,2β,3α,5α)>-2-(methoxymethyl)-3,5-bis(phenylmethoxy)cyclopentanemethanol

Toluene-4-sulfonic acid (1S,2S,3R,5S)-3,5-bis-benzyloxy-2-methoxymethyl-cyclopentylmethyl ester

<1R-(1α,2β,3α,5α)>-2-methoxymethyl-3,5-bis(phenylmethoxy)cyclopentaneacetonitrile