[1,1'-Biphenyl]-2-ethanol

Base Information

• Chemical Name: [1,1'-Biphenyl]-2-ethanol
• CAS No.: 111033-77-3
• Molecular Formula: C14H14O
• Molecular Weight: 198.265
• Mol file: 111033-77-3.mol

Synonyms:

Chemical Property of [1,1'-Biphenyl]-2-ethanol

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [1,1'-Biphenyl]-2-ethanol

There total 1 articles about [1,1'-Biphenyl]-2-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(2-bromophenyl)ethanoate (2178-24-7) → 2-[1,1'-biphenyl]-2-ylethanol (111033-77-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; 1,4-dioxane / 24 h / 80 °C / Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 0.75 h / 0 - 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; 1,4-dioxane; water;

Reference yield: 100.0%

Succinimide (123-56-8,89963-74-6) + 2-[1,1'-biphenyl]-2-ylethanol (111033-77-3) → C18H17NO2 (1281027-45-9)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 0 - 20 ℃;

DOI:10.1039/c0ob00559b

Reference yield:

2-[1,1'-biphenyl]-2-ylethanol (111033-77-3) → 4-phenyl-5,12b-dihydro-6H-isoindolo[1,2-a]isoquinolin-8-one

Guidance literature:

Multi-step reaction with 3 steps

1: triphenylphosphine; diethylazodicarboxylate / dichloromethane / 0 - 20 °C

2: sodium tetrahydroborate; potassium hydrogencarbonate / ethanol; water / 0 - 5 °C

3: trifluorormethanesulfonic acid / chloroform / Reflux

With sodium tetrahydroborate; trifluorormethanesulfonic acid; potassium hydrogencarbonate; triphenylphosphine; diethylazodicarboxylate; In ethanol; dichloromethane; chloroform; water; 1: Mitsunobu reaction;

DOI:10.1039/c0ob00559b

upstream raw materials:

ethyl 2-(2-bromophenyl)ethanoate

Downstream raw materials:

C₁₈H₁₇NO₂

C₁₈H₁₉NO₂

Refernces