Technology Process of C26H21N3O3
There total 6 articles about C26H21N3O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 16h;
Inert atmosphere;
DOI:10.1016/j.bmcl.2012.10.046
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium hydroxide monohydrate / water; tetrahydrofuran / 8 h / 20 °C / Inert atmosphere
2: Polyphosphoric acid trimethylsilyl ester / 5 h / 140 °C / Inert atmosphere
3: acetic acid; hydrogenchloride / water / 4 h / Inert atmosphere; Reflux
4: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; dmap / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
With
hydrogenchloride; dmap; lithium hydroxide monohydrate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; acetic acid;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.10.046
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Polyphosphoric acid trimethylsilyl ester / 5 h / 140 °C / Inert atmosphere
2: acetic acid; hydrogenchloride / water / 4 h / Inert atmosphere; Reflux
3: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; dmap / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
With
hydrogenchloride; dmap; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; acetic acid;
In
water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.10.046