N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine

Base Information

Chemical Name:N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine
CAS No.:882084-07-3
Molecular Formula:C₁₆H₁₄N₄O₄
Molecular Weight:326.312
Hs Code.:
DSSTox Substance ID:DTXSID501326028
ChEMBL ID:CHEMBL1387869
Mol file:882084-07-3.mol

Synonyms:N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine;882084-07-3;MLS000721787;N-(2,4-dimethoxyphenyl)-6-nitro-4-quinazolinamine;CHEMBL1387869;DTXSID501326028;HMS2718H19;AKOS002350809;JS-2166;SMR000336941;SR-01000309715;SR-01000309715-1

Suppliers and Price of N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(2,4-DIMETHOXYPHENYL)-6-NITRO-4-QUINAZOLINAMINE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
N-(2,4-DIMETHOXYPHENYL)-6-NITRO-4-QUINAZOLINAMINE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
N-(2,4-DIMETHOXYPHENYL)-6-NITRO-4-QUINAZOLINAMINE 95.00%
1MG
$ 647.61

Total 0 raw suppliers

Chemical Property of N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine

Chemical Property:

Boiling Point:507.8±50.0 °C(Predicted)
PKA:5.44±0.50(Predicted)
Density:1.383±0.06 g/cm3(Predicted)
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:326.10150494
Heavy Atom Count:24
Complexity:433

Purity/Quality:: N-(2,4-DIMETHOXYPHENYL)-6-NITRO-4-QUINAZOLINAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)NC2=NC=NC3=C2C=C(C=C3)[N+](=O)[O-])OC

Technology Process of N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine

There total 2 articles about N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 22363-16-2
ethyl N-(2-cyano-4-nitrophenyl)formimidate

: 2735-04-8,161687-55-4
2,4-Dimethoxyaniline

: 882084-07-3
N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine

Guidance literature:: With acetic acid; for 1h; Reflux;
DOI:10.1039/c3md00118k

Reference yield:

: 17420-30-3
5-nitroanthranilonitrile

: 882084-07-3
N-(2,4-dimethoxyphenyl)-6-nitroquinazolin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride / 24 h / Reflux

2: acetic acid / 1 h / Reflux

With acetic anhydride; acetic acid; 2: |Dimroth Rearrangement;
DOI:10.1039/c3md00118k