C₂₉H₄₂N₆O₃S

Base Information

• Chemical Name: C₂₉H₄₂N₆O₃S
• CAS No.: 1304723-91-8
• Molecular Formula: C₂₉H₄₂N₆O₃S
• Molecular Weight: 554.757
• Mol file: 1304723-91-8.mol

Synonyms:

Chemical Property of C₂₉H₄₂N₆O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₄₂N₆O₃S

There total 15 articles about C₂₉H₄₂N₆O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H19NO3S (1304723-89-4) + C15H23N5 (1304723-54-3) → C29H42N6O3S (1304723-91-8)

Guidance literature:

With triethylamine; In ethanol; at 55 ℃;

DOI:10.1016/j.bmcl.2011.02.098

Reference yield:

(S)-7-benzyl-2,7-diazaspiro[4.5]decane (1304723-50-9) → C29H42N6O3S (1304723-91-8)

Guidance literature:

Multi-step reaction with 5 steps

1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 1 h / 80 °C

2: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / 7 h / 95 °C

3: hydroxylamine hydrochloride; sodium acetate / methanol / 16 h / 20 °C

4: palladium 10% on activated carbon; ammonium formate / methanol / 16 h / Reflux

5: triethylamine / ethanol / 55 °C

With palladium 10% on activated carbon; hydroxylamine hydrochloride; ammonium formate; sodium acetate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; N-ethyl-N,N-diisopropylamine; sodium t-butanolate; In 1-methyl-pyrrolidin-2-one; methanol; ethanol; 2: Buchwald coupling;

DOI:10.1016/j.bmcl.2011.02.098

Reference yield:

C22H27ClN4 (1304723-51-0) → C29H42N6O3S (1304723-91-8)

Guidance literature:

Multi-step reaction with 4 steps

1: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / 7 h / 95 °C

2: hydroxylamine hydrochloride; sodium acetate / methanol / 16 h / 20 °C

3: palladium 10% on activated carbon; ammonium formate / methanol / 16 h / Reflux

4: triethylamine / ethanol / 55 °C

With palladium 10% on activated carbon; hydroxylamine hydrochloride; ammonium formate; sodium acetate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; sodium t-butanolate; In methanol; ethanol; 1: Buchwald coupling;

DOI:10.1016/j.bmcl.2011.02.098

upstream raw materials:

4,6-dichloro-5-cyclopropylpyrimidine

(S)-7-benzyl-2,7-diazaspiro[4.5]decane

C₂₂H₂₇ClN₄

C₃₅H₃₇N₅