2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide

Base Information

Chemical Name:2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide
CAS No.:1349649-75-7
Molecular Formula:C₂₀H₂₃F₆N₅O₂S
Molecular Weight:511.491
Hs Code.:

2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide

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Chemical Property of 2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide

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Technology Process of 2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide

There total 2 articles about 2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 764667-65-4
1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione

: 1349649-75-7
2-methylpropane-2-suIfinic acid [(R)-3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)propyl]amide

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / toluene / Reflux

2: sodium tetrahydroborate; acetic acid / dichloromethane / 0.5 h

3: isopropyl alcohol

With sodium tetrahydroborate; acetic acid; toluene-4-sulfonic acid; In dichloromethane; isopropyl alcohol; toluene;