Ethyl 2-(4-methoxyphenoxy)propanoate

Base Information

Chemical Name:Ethyl 2-(4-methoxyphenoxy)propanoate
CAS No.:111479-08-4
Molecular Formula:C₁₂H₁₆O₄
Molecular Weight:224.257
Hs Code.:
DSSTox Substance ID:DTXSID80603351
Mol file:111479-08-4.mol

Synonyms:Ethyl 2-(4-methoxyphenoxy)propanoate;111479-08-4;Propanoic acid, 2-(4-methoxyphenoxy)-, ethyl ester;2-(4-Methoxyphenoxy)-propionic Acid Ethyl Ester;SCHEMBL5112826;DTXSID80603351;ZGFMBUHREWMBOI-UHFFFAOYSA-N;Ethyl2-(4-methoxyphenoxy)propanoate;AKOS009165913

Suppliers and Price of Ethyl 2-(4-methoxyphenoxy)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl 2-(4-methoxyphenoxy)propanoate

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:224.10485899
Heavy Atom Count:16
Complexity:209

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)OC1=CC=C(C=C1)OC

Technology Process of Ethyl 2-(4-methoxyphenoxy)propanoate

There total 8 articles about Ethyl 2-(4-methoxyphenoxy)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 150-76-5
4-methoxy-phenol

: 535-11-5,41978-69-2
Ethyl 2-bromopropionate

: 111479-08-4,958238-90-9
ethyl 2-(4-methoxyphenoxy)propanoate

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃; for 14h;
DOI:10.1021/jo034253x

Reference yield: 71.0%

: 6111-99-5
ethyl diazoalaninate

: 150-76-5
4-methoxy-phenol

: 111479-08-4,958238-90-9
ethyl 2-(4-methoxyphenoxy)propanoate

Guidance literature:: With rubidium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; tetrakis(acetonitrile)copper(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; C₂₀H₃₆N₂O₇; In chloroform; at 40 ℃; for 2.5h; Inert atmosphere; Schlenk technique; Molecular sieve;
DOI:10.1039/d0cc00224k

Reference yield:

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 111479-08-4,958238-90-9
ethyl 2-(4-methoxyphenoxy)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene; 4-acetamidobenzenesulfonyl azide / acetonitrile / 9 h / 0 - 20 °C / Inert atmosphere

2: C₂₀H₃₆N₂O₇; tetrakis(acetonitrile)copper(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; rubidium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate / chloroform / 2.5 h / 40 °C / Inert atmosphere; Schlenk technique; Molecular sieve

With rubidium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; tetrakis(acetonitrile)copper(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; 4-acetamidobenzenesulfonyl azide; C₂₀H₃₆N₂O₇; 1,8-diazabicyclo[5.4.0]undec-7-ene; In chloroform; acetonitrile;
DOI:10.1039/d0cc00224k