5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin

Base Information

Chemical Name:5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin
CAS No.:112078-72-5
Molecular Formula:C₁₆H₁₂O₆
Molecular Weight:300.268
Hs Code.:
DSSTox Substance ID:DTXSID30432350
Nikkaji Number:J788.629B
Wikidata:Q82246423
Metabolomics Workbench ID:23048
ChEMBL ID:CHEMBL486219

Synonyms:coutareagenin

Suppliers and Price of 5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:300.06338810
Heavy Atom Count:22
Complexity:462

Purity/Quality:: ≥98% （HPLC） ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C2C(=CC(=O)OC2=C1)C3=CC(=C(C=C3)O)O)O

Technology Process of 5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin

There total 7 articles about 5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(3,4-Diisopropoxy-phenyl)-5-hydroxy-7-methoxy-chromen-2-one

: 112078-72-5
5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzopyran-2-one

Guidance literature:: With boron trichloride; In dichloromethane; for 1h; Ambient temperature;
DOI:10.1016/S0031-9422(00)84609-9

Reference yield:

: 2174-64-3
5-methoxyresorcinol

: 112078-72-5
5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzopyran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / ethanol / 72 h / Ambient temperature

2: BCl₃ / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; boron trichloride; In ethanol; dichloromethane;
DOI:10.1016/S0031-9422(00)84609-9

Reference yield:

: 3,4-diisopropyloxybenzoylethylacetate

: 112078-72-5
5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzopyran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / ethanol / 72 h / Ambient temperature

2: BCl₃ / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; boron trichloride; In ethanol; dichloromethane;
DOI:10.1016/S0031-9422(00)84609-9