(-)-Macronecine

Base Information

Chemical Name:(-)-Macronecine
CAS No.:21823-66-5
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
UNII:J7G72AJ4V7
Nikkaji Number:J2.134.067G

Synonyms:(-)-Macronecine;Macronecine, (-)-;J7G72AJ4V7;(1R,2S,7aS)-Hexahydro-2-hydroxy-1H-pyrrolizine-1-methanol;1H-Pyrrolizine-1-methanol, hexahydro-2-hydroxy-, (1R,2S,7aS)-;1H-Pyrrolizine-1-methanol, hexahydro-2-hydroxy-, [1R-(1alpha,2alpha,7aalpha)]-;21823-66-5

Suppliers and Price of (-)-Macronecine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (-)-Macronecine

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.110278721
Heavy Atom Count:11
Complexity:151

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2C(C(CN2C1)O)CO
Isomeric SMILES:C1C[C@H]2[C@@H]([C@@H](CN2C1)O)CO

Technology Process of (-)-Macronecine

There total 22 articles about (-)-Macronecine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: C₂₄H₃₃NO₂Si

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
rac-(1S,2S,7aR)-1-(hydroxymethyl)hexahydro-1H-pyrrolizin-2-ol

Guidance literature:: C₂₄H₃₃NO₂Si; With hydrogenchloride; methanol; for 1.5h;

With ammonium hydroxide; In water;
DOI:10.1016/j.tet.2009.01.085

Reference yield: 70.0%

: (1R*,2R*,6aR*)-methyl 2-hydroxy-3-oxo-hexahydro-1H-pyrrolizine-1-carboxylate

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
(+/-)-Macronecin

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 17h; Reflux;
DOI:10.1039/C6OB01871H

Reference yield: 62.0%

: C₂₄H₃₃NO₂Si

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
(+/-)-Macronecin

Guidance literature:: C₂₄H₃₃NO₂Si; With hydrogenchloride; methanol; for 1.5h;

With ammonium hydroxide; In water;
DOI:10.1016/j.tet.2009.01.085