(R)-ethyl 3,4-dihydroxybutanoate

Base Information Edit

Chemical Name:(R)-ethyl 3,4-dihydroxybutanoate
CAS No.:112635-76-4
Molecular Formula:C6H12O4
Molecular Weight:148.159
Hs Code.:
Mol file:112635-76-4.mol

Synonyms:.3(S)-4-dihydroxy-butyric acid ethyl ester;.ethyl (3S)-3,4-dihydroxybutyrate;.Ethyl (S)-3,4-dihydroxybutanoate;(S)-ethyl 3,4-dihydroxybutanoate;

Suppliers and Price of (R)-ethyl 3,4-dihydroxybutanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (R)-ethyl 3,4-dihydroxybutanoate Edit

Chemical Property:

Boiling Point:278.7±25.0 °C(Predicted)
PKA:13?+-.0.20(Predicted)
PSA：66.76000
Density:1.171±0.06 g/cm3(Predicted)
LogP:-0.70720

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (R)-3,4-Dihydroxybutanoic Acid Ethyl Ester is a reagent in the preparation of fostriecin. Also used in the synthesis of Coreoside D.

Technology Process of (R)-ethyl 3,4-dihydroxybutanoate

There total 12 articles about (R)-ethyl 3,4-dihydroxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 691-84-9
Diethyl (S)-malate

: 112635-76-4,108585-47-3
(S)-ethyl 3,4-dihydroxybutanoate

Guidance literature:: Diethyl (S)-malate; With dimethylsulfide borane complex; In tetrahydrofuran; for 1h; Inert atmosphere;

With sodium tetrahydroborate; In tetrahydrofuran; at 0 - 25 ℃; for 12h; Inert atmosphere;
DOI:10.1002/ejoc.202001563

Reference yield: 92.0%

: 32223-97-5
(+/-)-ethyl-3,4-epoxybutanoate

: 112083-64-4
ethyl 2-((2R)-oxiran-2-yl)acetate

: 112635-76-4,108585-47-3
(S)-ethyl 3,4-dihydroxybutanoate

Guidance literature:: With (1R,2R)-(-)-N,N'-bis(3,5-di-tert-butylsalicydene)-1,2-cyclohexanediaminocobalt(II); air; acetic acid; In tetrahydrofuran; at 0 - 20 ℃; for 16h;
DOI:10.1021/ja016737l

Reference yield: 90.0%

: 85518-49-6
ethyl γ-hydroxyacetoacetate

: 112635-76-4,108585-47-3
(S)-ethyl 3,4-dihydroxybutanoate

Guidance literature:: With D-glucose; broth E_. coli HB₁₀₁; pNTS₁G; NADP; In various solvent(s); at 30 ℃; for 20h; pH=6.5; Enzymatic reaction;
DOI:10.1016/S0957-4166(01)00279-8