4-CHLORO-2-NITRO-6-[1-(PHENYLIMINO)ETHYL]-PHENOL

Base Information

• Chemical Name: 4-CHLORO-2-NITRO-6-[1-(PHENYLIMINO)ETHYL]-PHENOL
• CAS No.: 112932-66-8
• Molecular Formula: C₁₄H₁₁ClN₂O₃
• Molecular Weight: 290.706
• Mol file: 112932-66-8.mol

Synonyms:4-chloro-2-nitro-6-[1-(phenylimino)ethyl]-phenol;2-hydroxy-3-nitro-5-chloroacetophenone anil;

Chemical Property of 4-CHLORO-2-NITRO-6-[1-(PHENYLIMINO)ETHYL]-PHENOL

Chemical Property:

• Vapor Pressure: 2.85E-06mmHg at 25°C
• Melting Point: 102 °C(Solv: ethanol (64-17-5))
• Boiling Point: 378.6oC at 760 mmHg
• PKA: 2.29±0.40(Predicted)
• Flash Point: 182.8oC
• PSA: 78.41000
• Density: 1.34g/cm3
• LogP: 4.61770

Purity/Quality:

4-CHLORO-2-NITRO-6-[1-(PHENYLIMINO)ETHYL]-PHENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-2-NITRO-6-[1-(PHENYLIMINO)ETHYL]-PHENOL

There total 1 articles about 4-CHLORO-2-NITRO-6-[1-(PHENYLIMINO)ETHYL]-PHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5′‐chloro‐2′‐hydroxy‐3′‐nitroacetophenone (84942-40-5) + aniline (62-53-3) → 2-hydroxy-3-nitro-5-chloroacetophenone anil (112932-66-8)

Guidance literature:

In benzene; for 6h; Heating;

Reference yield: 40.0%

mercaptoacetic acid (68-11-1) + 2-hydroxy-3-nitro-5-chloroacetophenone anil (112932-66-8) → α-methyl-2-(2'-hydroxy-3'-nitro-5'-chlorophenyl)-3-phenyl-4-thiazolidinone

Guidance literature:

In benzene; Heating;

Reference yield: 30.0%

DL-thiomalic acid (70-49-5,644-87-1) + 2-hydroxy-3-nitro-5-chloroacetophenone anil (112932-66-8) → α-methyl-2-(2'-hydroxy-3'-nitro-5'-chlorophenyl)-3-phenyl-5-carboxymethyl-4-thiazolidinone

Guidance literature:

With zinc(II) chloride; at 160 ℃;

upstream raw materials:

5′‐chloro‐2′‐hydroxy‐3′‐nitroacetophenone

aniline