3-Chlorocarbonyl-but-3-enoic acid vinyl ester

Base Information

• Chemical Name: 3-Chlorocarbonyl-but-3-enoic acid vinyl ester
• CAS No.: 85753-86-2
• Molecular Formula: C₇H₇ClO₃
• Molecular Weight: 174.584
• Mol file: 85753-86-2.mol

Synonyms:

Chemical Property of 3-Chlorocarbonyl-but-3-enoic acid vinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Chlorocarbonyl-but-3-enoic acid vinyl ester

There total 2 articles about 3-Chlorocarbonyl-but-3-enoic acid vinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-vinyl itaconate (85753-88-4) → 3-Chlorocarbonyl-but-3-enoic acid vinyl ester (85753-86-2)

Guidance literature:

With thionyl chloride; In dichloromethane; N,N-dimethyl-formamide; for 6h; Heating;

DOI:10.1021/jo00366a023

Reference yield:

2-methylenesuccinic acid (97-65-4,25119-64-6) → 3-Chlorocarbonyl-but-3-enoic acid vinyl ester (85753-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 16 percent / Hg(OAc)2 / tetrahydrofuran / 16 h / Ambient temperature

2: SOCl₂ / CH₂Cl₂; dimethylformamide / 6 h / Heating

With thionyl chloride; mercury(II) diacetate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo00366a023

Reference yield:

3-Chlorocarbonyl-but-3-enoic acid vinyl ester (85753-86-2) + butan-1-ol (71-36-3) → 1-n-butyl 4-vinyl itaconate (102651-52-5)

Guidance literature:

With triethylamine; In diethyl ether; at 0 ℃; for 1h; Yield given;

DOI:10.1021/jo00366a023

upstream raw materials:

4-vinyl itaconate

2-methylenesuccinic acid

Downstream raw materials:

1-n-butyl 4-vinyl itaconate