C₂₃H₂₁N₅O₅S

Base Information

• Chemical Name: C₂₃H₂₁N₅O₅S
• CAS No.: 1320269-93-9
• Molecular Formula: C₂₃H₂₁N₅O₅S
• Molecular Weight: 479.516
• Mol file: 1320269-93-9.mol

Synonyms:

Chemical Property of C₂₃H₂₁N₅O₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₁N₅O₅S

There total 10 articles about C₂₃H₂₁N₅O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H8O2S (1206885-89-3) → C23H21N5O5S (1320269-93-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / 4 h / 0 °C / Inert atmosphere

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere

2.2: 4 h / -70 °C / Inert atmosphere

3.1: N-iodo-succinimide / dichloromethane; acetonitrile / 19 h / 0 °C / Inert atmosphere

4.1: triethyl borane; oxygen; tri-n-butyl-tin hydride / tetrahydrofuran; toluene / 18 h / -70 °C

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

6.1: tetrahydrofuran / 18 h / Inert atmosphere

With 1H-imidazole; N-iodo-succinimide; triethyl borane; tetrabutyl ammonium fluoride; oxygen; tri-n-butyl-tin hydride; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;

DOI:10.1021/ml2001054

Reference yield:

1,4-anhydro-4-C-ethynyl-2,3-O-isopropylidene-4-thio-D-ribitol (1206885-88-2) → C23H21N5O5S (1320269-93-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: tetrahydrofuran; pentane / 15 h / -70 °C / Inert atmosphere

2.1: 1H-imidazole / N,N-dimethyl-formamide / 4 h / 0 °C / Inert atmosphere

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere

3.2: 4 h / -70 °C / Inert atmosphere

4.1: N-iodo-succinimide / dichloromethane; acetonitrile / 19 h / 0 °C / Inert atmosphere

5.1: triethyl borane; oxygen; tri-n-butyl-tin hydride / tetrahydrofuran; toluene / 18 h / -70 °C

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

7.1: tetrahydrofuran / 18 h / Inert atmosphere

With 1H-imidazole; N-iodo-succinimide; triethyl borane; tetrabutyl ammonium fluoride; oxygen; tri-n-butyl-tin hydride; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile; pentane;

DOI:10.1021/ml2001054

Reference yield:

1,4-anhydro-5-O-(t-butyldimethylsilyloxymethyl)-4-C-formyl-2,3-O-isopropylidene-4-thio-D-ribitol (1206885-82-6) → C23H21N5O5S (1320269-93-9)

Guidance literature:

Multi-step reaction with 8 steps

1.1: potassium carbonate / methanol / 20 h / 0 °C / Inert atmosphere

1.2: 16 h / 0 °C

2.1: tetrahydrofuran; pentane / 15 h / -70 °C / Inert atmosphere

3.1: 1H-imidazole / N,N-dimethyl-formamide / 4 h / 0 °C / Inert atmosphere

4.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere

4.2: 4 h / -70 °C / Inert atmosphere

5.1: N-iodo-succinimide / dichloromethane; acetonitrile / 19 h / 0 °C / Inert atmosphere

6.1: triethyl borane; oxygen; tri-n-butyl-tin hydride / tetrahydrofuran; toluene / 18 h / -70 °C

7.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

8.1: tetrahydrofuran / 18 h / Inert atmosphere

With 1H-imidazole; N-iodo-succinimide; triethyl borane; tetrabutyl ammonium fluoride; oxygen; tri-n-butyl-tin hydride; potassium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile; pentane;

DOI:10.1021/ml2001054

upstream raw materials:

1,4-anhydro-5-O-(t-butyldimethylsilyloxymethyl)-4-C-formyl-2,3-O-isopropylidene-4-thio-D-ribitol

1,4-anhydro-4-C-ethynyl-2,3-O-isopropylidene-4-thio-D-ribitol

C₇H₈O₂S

C₁₉H₃₄O₃SSi₂