3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide

Base Information

• Chemical Name: 3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide
• CAS No.: 1256601-52-1
• Molecular Formula: C₃₇H₃₇F₆N₇O₂S
• Molecular Weight: 757.803
• Mol file: 1256601-52-1.mol

Synonyms:

Chemical Property of 3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide

There total 1 articles about 3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H34N6O2 + 3,5-bistrifluoromethylphenylisothiocyanate (23165-29-9) → 3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide (1256601-52-1)

Guidance literature:

In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.3390/molecules15118327

Reference yield:

3-[[5-[2-[[(1R,2R)-2-[3-(3,5-bis(trifluoromethyl)phenyl)thioureido]cyclohexyl](methyl)amino]ethyl]-1H-1,2,3-triazol-1-yl]methyl]-N-cinnamoylbenzamide (1256601-52-1) + malononitrile (109-77-3) → C40H39F6N9O2S (1256601-53-2) + C40H39F6N9O2S

Guidance literature:

In dichloromethane; at 20 ℃; for 48h; optical yield given as %de; stereoselective reaction; Inert atmosphere;

DOI:10.3390/molecules15118327

upstream raw materials:

3,5-bistrifluoromethylphenylisothiocyanate

Downstream raw materials:

C₄₀H₃₉F₆N₉O₂S