<7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin

Base Information

Chemical Name:<7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin
CAS No.:88480-54-0
Molecular Formula:C₄₂H₆₄N₁₂O₁₂S₂
Molecular Weight:993.175
Hs Code.:

Synonyms:

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Chemical Property of <7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin

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Technology Process of <7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin

There total 9 articles about <7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Cysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-cysteinyl-<2-(3-aminopyrrolidin-2-on-1yl)-4-methylpentanoyl>glycine Amide

: 88480-54-0
<7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin

Guidance literature:: With potassium hexacyanoferrate(III); In water; for 1h; Further byproducts given. Yields of byproduct given; Ambient temperature; pH = 7;
DOI:10.1135/cccc19840642

Reference yield:

: 88463-36-9
N^α-Benzyloxycarbonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-<2-(3-aminopyrrolidin-2-on-1yl)-4-methylpentanoyl>glycine Amide

: 88480-54-0
<7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin

Guidance literature:: Multi-step reaction with 2 steps

1: 1) Sodium, 2) acetic acid / liquid ammonia

2: 9 mg / K₃Fe(CN)6 / H₂O / 1 h / Ambient temperature; pH = 7

With sodium; acetic acid; potassium hexacyanoferrate(III); In ammonia; water;
DOI:10.1135/cccc19840642

Reference yield:

: 106749-34-2
2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoyl-glycine Amide

: 88480-54-0
<7,8-2-(3-Aminopyrrolidin-2-on-1-yl)-4-methylpentanoic acid>oxytocin

Guidance literature:: Multi-step reaction with 3 steps

1: 83 mg / 1) N-hydroxybenzotriazol, 2) dicyclohexylcarbodiimide / dimethylformamide / 1) Room temp. 2) -lO deg C, 1 h, 3) room temp. 40 h

2: 1) Sodium, 2) acetic acid / liquid ammonia

3: 9 mg / K₃Fe(CN)6 / H₂O / 1 h / Ambient temperature; pH = 7

With sodium; benzotriazol-1-ol; acetic acid; dicyclohexyl-carbodiimide; potassium hexacyanoferrate(III); In ammonia; water; N,N-dimethyl-formamide;
DOI:10.1135/cccc19840642