2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole

Base Information

• Chemical Name: 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole
• CAS No.: 157771-53-4
• Molecular Formula: C₂₉H₂₆N₂O
• Molecular Weight: 418.538
• Mol file: 157771-53-4.mol

Synonyms:

Chemical Property of 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole

There total 4 articles about 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

(4'-methoxy-4-biphenylyl)magnesium bromide + 2-(4-bromophenyl)-1-propylbenzimidazole (157771-52-3) → 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole (157771-53-4)

Guidance literature:

With [1,4-bis(diphenylphosphino)butane] palladium(ll) dichloride; In various solvent(s); for 2h; Heating;

Reference yield:

2-(4-bromophenyl)-1H-benzimidazole (2622-74-4) → 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole (157771-53-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / 50percent aq. NaOH / acetone / 14 h / Heating

2: 40 percent / palladium(II) chloride 1,4-bis(diphenylphosphino)butane / various solvent(s) / 2 h / Heating

With sodium hydroxide; [1,4-bis(diphenylphosphino)butane] palladium(ll) dichloride; In acetone;

Reference yield:

4-Bromobenzoic acid (586-76-5) → 2-(4''-methoxyterphenyl-4-yl)-1-propylbenzimidazole (157771-53-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 60 percent / plyphosphoric acid / 6 h / 210 °C

2: 55 percent / 50percent aq. NaOH / acetone / 14 h / Heating

3: 40 percent / palladium(II) chloride 1,4-bis(diphenylphosphino)butane / various solvent(s) / 2 h / Heating

With sodium hydroxide; [1,4-bis(diphenylphosphino)butane] palladium(ll) dichloride; plyphosphoric acid; In acetone;

upstream raw materials:

2-(4-bromophenyl)-1-propylbenzimidazole

2-(4-bromophenyl)-1H-benzimidazole

4-Bromobenzoic acid

1,2-diamino-benzene