5-hexanolide

Base Information

• Chemical Name: 5-hexanolide
• CAS No.: 26991-67-3
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.144
• Mol file: 26991-67-3.mol

Synonyms:

Chemical Property of 5-hexanolide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-hexanolide

There total 66 articles about 5-hexanolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-Methylcyclopentanone (1120-72-5) → 5-hexanolide (823-22-3,26991-67-3)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid;

DOI:10.1021/jo9515081

Reference yield: 97.0%

hexane-1,5-diol (928-40-5) → 5-hexanolide (823-22-3,26991-67-3)

Guidance literature:

With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; In acetonitrile; at 22 ℃; for 6h;

DOI:10.1021/jacs.5b01036

Reference yield: 92.0%

5-ketohexanoic acid (3128-06-1) → 5-hexanolide (823-22-3,26991-67-3)

Guidance literature:

With (dipyridylamine)Cp*IrOSO₃; hydrogen; In water; at 130 ℃; for 32h; under 3750.38 Torr;

DOI:10.1021/acs.organomet.7b00503

upstream raw materials:

3,4-dihydro-6-methyl-2H-pyran-2-one

acetic anhydride

5-ketohexanoic acid

chloropropionic acid

Downstream raw materials:

5-oxo-hexanoic acid amide

δ-Acetoxy-capronsaeuremethylester

5--pentan-2-ol

hexane-1,5-diol