methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside

Base Information

• Chemical Name: methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside
• CAS No.: 78797-79-2
• Molecular Formula: C₃₇H₄₆O₂₀S₂
• Molecular Weight: 874.892
• Mol file: 78797-79-2.mol

Synonyms:

Chemical Property of methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside

There total 3 articles about methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methyl 2,4-di-O-acetyl-3-O-(2,3,4-tri-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside (78797-78-1) + p-toluenesulfonyl chloride (98-59-9) → methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside (78797-79-2)

Guidance literature:

In pyridine; Ambient temperature;

DOI:10.1016/S0008-6215(00)80762-4

Reference yield: 70.0%

methyl β-D-glucopyranosyl-(1->3)-β-D-glucopyranoside (7115-19-7,15038-72-9,18449-79-1,52492-55-4,68709-26-2,70428-29-4,71117-17-4,72028-62-7,80286-86-8,81131-46-6,84049-77-4,84063-96-7,85439-69-6,101144-27-8,104420-77-1,104714-42-3,108449-65-6,114375-70-1,114375-71-2,117064-56-9,117064-57-0,117466-15-6,117605-36-4,124580-30-9,125412-00-2,125412-01-3,127641-08-1,128443-50-5,130009-32-4,130009-33-5,144490-62-0) + p-toluenesulfonyl chloride (98-59-9) → methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside (78797-79-2)

Guidance literature:

In pyridine; 1.) 1 h, -20 deg C; 2.) 0 deg C, overnight;

DOI:10.1016/S0008-6215(00)80762-4

Reference yield:

methyl 2,4-di-O-acetyl-3-O-(2,3,4-tri-O-acetyl-6-O-trityl-β-D-glucopyranosyl)-6-O-trityl-β-D-glucopyranoside (78797-77-0) → methyl 2,4-di-O-acetyl-6-O-p-tolylsulfonyl-3-O-(2,3,4-tri-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranosyl)-β-D-glucopyranoside (78797-79-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / aq. acetic acid / 2.5 h / 70 °C

2: 91 percent / pyridine / Ambient temperature

In pyridine; acetic acid;

DOI:10.1016/S0008-6215(00)80762-4

upstream raw materials:

methyl β-D-glucopyranosyl-(1->3)-β-D-glucopyranoside

p-toluenesulfonyl chloride

methyl 2,4-di-O-acetyl-3-O-(2,3,4-tri-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside

methyl 2,4-di-O-acetyl-3-O-(2,3,4-tri-O-acetyl-6-O-trityl-β-D-glucopyranosyl)-6-O-trityl-β-D-glucopyranoside