Benzeneacetic acid, 2-[(cyclohexylamino)carbonyl]hydrazide

Base Information

• Chemical Name: Benzeneacetic acid, 2-[(cyclohexylamino)carbonyl]hydrazide
• CAS No.: 114873-30-2
• Molecular Formula: C15H21N3O2
• Molecular Weight: 275.351
• Mol file: 114873-30-2.mol

Synonyms:

Chemical Property of Benzeneacetic acid, 2-[(cyclohexylamino)carbonyl]hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetic acid, 2-[(cyclohexylamino)carbonyl]hydrazide

There total 1 articles about Benzeneacetic acid, 2-[(cyclohexylamino)carbonyl]hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Cyclohexyl isocyanate (3173-53-3) + 2-phenylacetylhydrazine (937-39-3) → N4-cyclohexyl-phenylacetic acid semicarbazide (114873-30-2)

Guidance literature:

In N,N-dimethyl acetamide; at 20 ℃; for 24h;

Reference yield: 90.0%

N4-cyclohexyl-phenylacetic acid semicarbazide (114873-30-2) → 5-benzyl-4-cyclohexyl-2,4-dihydro-[1,2,4]triazol-3-one

Guidance literature:

With sodium hydroxide; for 2h; Heating;

Reference yield:

N4-cyclohexyl-phenylacetic acid semicarbazide (114873-30-2) → cyclohexyl-(5-benzyl-[1,3,4]oxadiazol-2-yl)-amine

Guidance literature:

With pyridine; p-toluenesulfonyl chloride; In tetrahydrofuran; at 65 - 70 ℃; for 20h;

DOI:10.1021/jo0618730

upstream raw materials:

Cyclohexyl isocyanate

2-phenylacetylhydrazine