Technology Process of Essigsaeure-<2-(3-hydroxy-1-octenyl)-4,6-bis((tetrahydropyran-2-yl)oxy)phenaethyl>ester
There total 12 articles about Essigsaeure-<2-(3-hydroxy-1-octenyl)-4,6-bis((tetrahydropyran-2-yl)oxy)phenaethyl>ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; zinc(II) chloride;
In
diethyl ether;
for 2h;
Ambient temperature;
DOI:10.1002/hlca.19800630612
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 260 g / benzene / 72 h / Ambient temperature
2: 220 g / 1N NaOH / methanol; H2O / 0.08 h
3: 76 g / CHCl3 / 48 h / Heating
4: 222 g / Pyridin / diethyl ether / 1.) 0 deg C, 2 h 2.) 10 deg C, 1 h
5: 182 g / ZnCl2, NaBH4 / diethyl ether / 2 h / Ambient temperature
With
pyridine; sodium hydroxide; sodium tetrahydroborate; zinc(II) chloride;
In
methanol; diethyl ether; chloroform; water; benzene;
DOI:10.1002/hlca.19800630612
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 130 g / LiBH4 / tetrahydrofuran / 1.) 2 h 2.) reflux, 4 h
2: 145 g / p-Toluolsulfonsaeure / benzene; tetrahydrofuran / 6 h
3: 98 g / Dibal / toluene / 2.5 h / -70 °C
4: 76 g / CHCl3 / 48 h / Heating
5: 222 g / Pyridin / diethyl ether / 1.) 0 deg C, 2 h 2.) 10 deg C, 1 h
6: 182 g / ZnCl2, NaBH4 / diethyl ether / 2 h / Ambient temperature
With
pyridine; sodium tetrahydroborate; lithium borohydride; diisobutylaluminium hydride; toluene-4-sulfonic acid; zinc(II) chloride;
In
tetrahydrofuran; diethyl ether; chloroform; toluene; benzene;
DOI:10.1002/hlca.19800630612
