(R)-[1-(ChloroMethyl)propyl]benzene

Base Information

• Chemical Name: (R)-[1-(ChloroMethyl)propyl]benzene
• CAS No.: 20068-14-8
• Molecular Formula: C₁₀H₁₃Cl
• Molecular Weight: 168.666
• Mol file: 20068-14-8.mol

Synonyms:

Chemical Property of (R)-[1-(ChloroMethyl)propyl]benzene

Chemical Property:

• Boiling Point: 102-103 °C(Press: 12 Torr)
• Density: 1.025 g/cm3(Temp: 25 °C)

Purity/Quality:

99% ^*data from raw suppliers

(R)-[1-(Chloromethyl)propyl]benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (R)-[1-(Chloromethyl)propyl]benzene is used in the synthesis of organotin compounds used as biochemical catalysts and intermediates.

Technology Process of (R)-[1-(ChloroMethyl)propyl]benzene

There total 3 articles about (R)-[1-(ChloroMethyl)propyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-phenylbutyric acid (4286-15-1) → (+)-(S)-1-Chlor-2-phenyl-butan (20068-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: SOCl₂, Py

With pyridine; lithium aluminium tetrahydride; thionyl chloride; In diethyl ether;

DOI:10.1021/jo01024a008

Reference yield:

(R)-2-phenyl-butan-1-ol (16460-75-6,89104-46-1) → (+)-(S)-1-Chlor-2-phenyl-butan (20068-14-8)

Guidance literature:

With thionyl chloride;

Reference yield:

(2R)-2-phenylbutanoic acid (938-79-4) → (+)-(S)-1-Chlor-2-phenyl-butan (20068-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄

2: SOCl₂

With lithium aluminium tetrahydride; thionyl chloride;

upstream raw materials:

(R)-2-phenyl-butan-1-ol

(2R)-2-phenylbutanoic acid

(S)-2-phenylbutyric acid

Downstream raw materials:

(S)-3-phenylvaleric acid

(+)(S)-5-Phenyl-hepten-⁽¹⁾

(+)-(S)-3-phenylpentan-1-ol

(S)-heptan-3-ylbenzene